Accuracy of Intraocular Lens Power in High Myopia
|ClinicalTrials.gov Identifier: NCT03394300|
Recruitment Status : Unknown
Verified January 2018 by salma safwat abdelhady mangora, Assiut University.
Recruitment status was: Not yet recruiting
First Posted : January 9, 2018
Last Update Posted : January 9, 2018
|Condition or disease||Intervention/treatment|
|High Myopia||Other: iol power calculation|
High myopia or pathological myopia is associated with elongation of axial length longer than 26 mm or refractive error at least-6 diopter.
High myopia is one of the most prevalent refractive condition globally with a higher risk of other eye conditions Moreover in high myopic eyes the incidence of cataract is significantly higher than in non myopic eyes and the progression is also faster.
Calculation of IOL in high myopic eyes remains a challenge often leading to unexpected postoperative hyperopia the main potential sources of errors in IOL calculation for high myopic eyes include AL measurement & IOL constants used &IOL power calculation formula used.
investigators suspect that the SRK I1 formula is inaccurate for myopic eyes, and that new formulas are needed, taking into account all those factors that make up the dioptric power of an eye.
Formulas for IOL power calculation had past four generations, first generation formulas were theoretical and based on the same fundamental constant with no respect to anterior chamber depth. Since then, Binkhorst, Holladay, Hoffer and Shammas had refined the existing theoretical formulas where each of them developed his regression formula based on analysis of their previous IOL cases .
This work was amalgamated in 1980 and yielded the Sanders Retzlaff Kraff I (SRKI) formula The second generation was designed by combining linear regression analysis and stepwise adjustment for long and short eyes according to anterior chamber depth .
The third and fourth generation formulas, started by Holladay in 1988, all aimed at better calculation of the IOL power in eyes with extreme axial length where another term had appeared which is IOL specific anterior chamber depth .
The accuracy of third and fourth generation formulas for IOL calculation in patients with high axial myopia had not been fully evaluated For that, the need for more studies conducted to evaluate such accuracy is crucial.
This study will be conducted to evaluate the accuracy of different formulas used for IOL power calculation in patients with high axial myopia undergoing cataract surgery
|Study Type :||Observational [Patient Registry]|
|Estimated Enrollment :||30 participants|
|Target Follow-Up Duration:||1 Year|
|Official Title:||Accuracy of Intraocular Lens Power in High Myopia|
|Estimated Study Start Date :||February 1, 2018|
|Estimated Primary Completion Date :||February 1, 2019|
|Estimated Study Completion Date :||February 1, 2019|
- Other: iol power calculation
iol power calculation in high myopia
- accuracy of iol power in high myopia [ Time Frame: one year ]biometry assment of IOLpower