Italian National Study on the Critically Ill Liver Transplant Patient With an Infection (INFE-OLT)
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ClinicalTrials.gov Identifier: NCT03363646
Recruitment Status : Unknown
Verified September 2018 by Gianni Biancofiore, University of Pisa. Recruitment status was: Recruiting
Despite major advances, infections remain one of the major causes of morbidity and mortality in patients undergoing orthotopic liver transplantation (OLT). Furthermore, data on the epidemiology, severity, and type of post-OLT infections nowadays available come from dated, monocentric, retrospective series. Finally, there is no available data focused on the critical OLT patient admitted to the Intensive Care Unit (ICU). Therefore this study was conceived (1) to describe incidence, severity, epidemiology and outcomes of infections recorded in OLT patients in the ICU (first or re-admission ); (2) to identify possible risk factors and (3) to report the type of the involved microorganism with their antibiotic sensitivity pattern
Condition or disease
Liver TransplantationInfectionSepsisIntensive Care Unit
The study will record clinical, epidemiological and microbiological data from the clinical files of OLT patients admitted at italian ICUs
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Layout table for eligibility information
Ages Eligible for Study:
Child, Adult, Older Adult
Sexes Eligible for Study:
liver transplant recipients
Age> 18 aa
written consent to participate in the study
having been undergone to OLT in the 10 years prior to enrollment
Infection diagnosis (any type, any localization, any agent)
Being admitted in the ICU
Exclusion criteria 1. Death within 72 hours of admission 2. Withdrawal of consent