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High-intensity Training Safely Improves Exercise Capacity in Heart, Lung, Kidney, and Liver Transplant Recipients: a Comparative Study

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ClinicalTrials.gov Identifier: NCT03329586
Recruitment Status : Completed
First Posted : November 6, 2017
Last Update Posted : November 7, 2017
Sponsor:
Information provided by (Responsible Party):
Universitaire Ziekenhuizen Leuven

Brief Summary:
The investigators will investigate whether high-intensity exercise training can safely improve physical performance in long-term stable heart, kidney, lung, and liver transplant recipients. Adult transplant recipients will participate in Transplantoux, a 6-month individualized home- and group-based training program, with the goal to cycle the Mont Ventoux in France. The investigators will do cardiopulmonary exercise testing : maximal oxygen consumption, maximal power and BMI.

Condition or disease Intervention/treatment Phase
Physical Activity After Organ Transplantation Other: High-intensity training Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 42 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: High-intensity Training Safely Improves Exercise Capacity in Heart, Lung, Kidney, and Liver Transplant Recipients
Actual Study Start Date : August 1, 2013
Actual Primary Completion Date : June 21, 2014
Actual Study Completion Date : July 31, 2014

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: Training Other: High-intensity training
6-month individualized home- and group-based training program with the goal to cycle the Mont Ventoux in France




Primary Outcome Measures :
  1. VO2max [ Time Frame: 6 months after start training ]
    Maximal oxygen consumption



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • minimum post-transplant period of 6 months
  • no acute rejection during the immediately preceding 6 months

Exclusion Criteria:

  • patients with cardiovascular or orthopedic contra-indications for intensive physical exercise

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03329586


Locations
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Belgium
UZLeuven
Leuven, Belgium, 3000
Sponsors and Collaborators
Universitaire Ziekenhuizen Leuven

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Responsible Party: Universitaire Ziekenhuizen Leuven
ClinicalTrials.gov Identifier: NCT03329586     History of Changes
Other Study ID Numbers: Exercise in transplantation
First Posted: November 6, 2017    Key Record Dates
Last Update Posted: November 7, 2017
Last Verified: October 2017

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Universitaire Ziekenhuizen Leuven:
maximum oxygen consumption
organ transplantation
physical fitness
rehabilitation