Narrative Comprehension by People With Acquired Brain Injury
|ClinicalTrials.gov Identifier: NCT03309930|
Recruitment Status : Unknown
Verified October 2017 by Kelly Knollman-Porter, Miami University.
Recruitment status was: Recruiting
First Posted : October 16, 2017
Last Update Posted : October 16, 2017
|Condition or disease||Intervention/treatment||Phase|
|Aphasia Traumatic Brain Injury||Behavioral: Comprehension Acquired Brain Injury||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||60 participants|
|Intervention Model:||Single Group Assignment|
|Intervention Model Description:||During Study 1 participants will be exposed to three different conditions: (a) written text only, (b) auditory synthetic speech output only and (c) a combined condition (written and auditory output). During Study 2 participants will be provided repeated exposure to synthetic speech. Participants can participate in 1 or both studies with 1 study results not being dependent on the other study. .|
|Masking:||None (Open Label)|
|Primary Purpose:||Supportive Care|
|Official Title:||Narrative Comprehension by People With Acquired Brain Injury|
|Actual Study Start Date :||October 6, 2017|
|Estimated Primary Completion Date :||October 6, 2018|
|Estimated Study Completion Date :||October 6, 2018|
Experimental: Comprehension Acquired Brain Injury
All participants will be exposed to 3 conditions: (a) written text, (b) auditory output (synthetic speech), and combined conditions for study 1. For study 2 participants will be repeatedly exposed to synthetic speech output to determine the influence on comprehension. Participants are not required to participate in both studies.
Behavioral: Comprehension Acquired Brain Injury
For study 1 participants will be exposed to 3 conditions as stated in previous descriptions and will last 1 to 2 sessions. Study 2 will begin with 1 session with the researcher lasting about 30 minutes. Then participants will be asked to complete practice at home for about 15 minutes each day for 2 weeks using a computer/iPad. Study 2 Post Testing and Maintenance Sessions 1 and 2: approximately 60 minutes per session.
- Comprehension Across Conditions (Study 1 of 2) [ Time Frame: Comprehension accuracy across conditions will be assessed over 1 to 2 days. ]Participants will answer 10 multiple choice questions regarding the information contained in each of the 12 stories presented in 3 conditions: (1) written text only (b) auditory output only and (c) combined written text and auditory output .
- Repeated Exposure to Digitized and Synthetic Speech (Study 2 of 2) [ Time Frame: 2 weeks ]Participants will answer 30 yes/no questions per session. Comprehension percentage accuracy will be measured over the course of 2 weeks
- Comprehension Generalization [ Time Frame: measured 1 week and 4 weeks post termination of treatment ]Participants will listen to two stories presented in synthetic, computer generated speech and answer comprehension questions about the content of the stories to determine auditory comprehension accuracy
- Perceived Comprehension Accuracy [ Time Frame: measured 1 week and 4 weeks post termination of treatment ]Participants will rate the accuracy and ease of comprehension of the sentences from each condition using a 5 point Likert scale.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03309930
|Contact: Kelly K Knollman-Porter, PhDemail@example.com|
|Contact: Sarah Wallace, PhDfirstname.lastname@example.org|
|Principal Investigator:||Kelly K Knollman-Porter, PhD||Miami University|
|Principal Investigator:||Sarah Wallace, PhD||Duquesne University|