Anastomotic Leakage After Anterior Resection of Rectal Cancer
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ClinicalTrials.gov Identifier: NCT03281070
Recruitment Status : Unknown
Verified September 2017 by Zhongtao Zhang, Beijing Friendship Hospital. Recruitment status was: Recruiting
Anastomotic leakage (AL) is one of the most-feared postoperative complications after anterior resection of rectal cancer. This complication compromises both short term and long term outcome of patients. The incidence of AL after anterior resection was approximately 6-11%. Although several risk factors for AL such as male sex, smoking, tumor location, longer operative time, intraoperative blood loss had been reported in previous studies, the incidence of AL did not meet a significant decrease. So far there is no multi-site observational study on incidence and risk factors of AL after anterior resection in China, therefore this study aims to work on this issue and provide evidence for clinical practice.
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Layout table for eligibility information
Ages Eligible for Study:
Child, Adult, Older Adult
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Rectal cancer patients who underwent anterior resection with or without postoperative anastomotic leakage
adenocarcinoma of the rectum by biopsy
anterior resection was performed
anastomosis using circular stapler
history of colorectal cancer surgery
emergency surgery because of bowel obstruction, bleeding or perforation