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Community Acquired Sepsis Cohort (CASC)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT03280992
Recruitment Status : Recruiting
First Posted : September 13, 2017
Last Update Posted : September 20, 2019
Sponsor:
Information provided by (Responsible Party):
Rennes University Hospital

Brief Summary:
The aim of this project is to constitute a prospective cohort of all the patients presenting to the adult emergencies of the University Hospital Centre (CHU) of Rennes for a septic syndrome of community origin.

Condition or disease
Severe Septic Syndrome Septic Shock

Detailed Description:
Severe septic syndrome (SSG) and septic shock (CS) are two frequent and serious complications of infectious diseases. In this context, the optimization of the management of septic patients from their reception in the emergency services must be a priority. However there are no predictors of progression or severity in patients admitted to emergencies despite the recommendations emphasizing the need for screening and early therapeutic management. Many scores have been proposed for intensive care unit but they remain difficult to extrapolate to other services because they are very comprehensive and require information that is difficult to obtain for emergency physicians.

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Study Type : Observational [Patient Registry]
Estimated Enrollment : 4500 participants
Observational Model: Cohort
Time Perspective: Prospective
Target Follow-Up Duration: 3 Months
Official Title: Community Acquired Sepsis Cohort
Actual Study Start Date : March 2, 2016
Estimated Primary Completion Date : December 31, 2019
Estimated Study Completion Date : December 31, 2019

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Sepsis




Primary Outcome Measures :
  1. Assessment of morbidity in patients with septic syndrome of community origin [ Time Frame: Day 90 ]
    Study of prognostic factors

  2. Internal validity, severity score [ Time Frame: Day 90 ]
  3. Internal validity, triage score by orientation nurses [ Time Frame: Day 90 ]
  4. Study of the prognostic factors of patients with septic syndrome of community origin in terms of mortality [ Time Frame: Day 90 ]


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patient with a community infectious diseases
Criteria

Inclusion Criteria:

  • Patient older than 18 years old
  • Patient hospitalized during the study period for community infectious diseases at the CHU of Rennes

Exclusion Criteria:

  • Written objection from the patient to the computer processing of his data
  • Pregnant women
  • Persons subject to major legal protection (safeguarding justice, guardianship, trusteeship), persons deprived of liberty

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03280992


Contacts
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Contact: Bruno Laviolle, MD, PhD 02.99.28.37.15 bruno.laviolle@chu-rennes.fr

Locations
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France
CHU de Rennes Recruiting
Rennes, France, 35033
Contact: Bruno Laviolle, MD, PhD    02.99.28.37.15    bruno.laviolle@chu-rennes.fr   
Sponsors and Collaborators
Rennes University Hospital
Additional Information:

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Responsible Party: Rennes University Hospital
ClinicalTrials.gov Identifier: NCT03280992    
Other Study ID Numbers: 35RC16_3024_CASC
First Posted: September 13, 2017    Key Record Dates
Last Update Posted: September 20, 2019
Last Verified: September 2019

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Shock, Septic
Systemic Inflammatory Response Syndrome
Sepsis
Infection
Inflammation
Pathologic Processes
Shock