Effect of Platelet Storage on Complement Activation
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03280823|
Recruitment Status : Unknown
Verified September 2017 by Shimaa Abdeleem, Assiut University.
Recruitment status was: Not yet recruiting
First Posted : September 13, 2017
Last Update Posted : September 13, 2017
|Condition or disease|
Ten units of platelets will be selected from the regular inventory of the Central Blood Transfusion Services/Assiut University Hospitals . All units of platelets will be collected, processed, and tested following the standard procedures.
Thesis units will be stored on a platelet rotator with the temperature controlled between 22 and 24c. Samples will be obtained using a sterile technique .
The investigators will take basal sample and samples on day 2,3,4 and 5. Complement components will be assayed : C4 (classical pathway), C3 (common pathway) and C5 (terminal pathway).
This evaluation will be done using ELISA technique
|Study Type :||Observational|
|Estimated Enrollment :||10 participants|
|Official Title:||Effect of Platelet Storage on Complement Activation|
|Estimated Study Start Date :||December 1, 2017|
|Estimated Primary Completion Date :||September 2018|
|Estimated Study Completion Date :||December 2018|
- Platelets can be used after storage upto 5 days instead of using in the same day of donation without complement activation. [ Time Frame: 5 days ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03280823
|Contact: Shimaa A Ahmedemail@example.com|
|Contact: Maha A Mahmoudfirstname.lastname@example.org|