The Effect of NVFS on GC in Individuals With DM: SR & MA of RCTs (NVFS&GC)
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|ClinicalTrials.gov Identifier: NCT03259724|
Recruitment Status : Unknown
Verified August 2017 by St. Michael's Hospital, Toronto.
Recruitment status was: Active, not recruiting
First Posted : August 24, 2017
Last Update Posted : August 24, 2017
Purpose of Study (The Effect of Non-Viscous Fibre Supplementation on Glycemic Control (NVFS & GC) in Individuals with Diabetes Mellitus.
Regardless of the remarkable advancement in pharmacotherapy, diabetes mellitus remains a major concern with more than 300 millions living with its complications including CVD. Nutrition is a cornerstone in diabetes management, and increasing total dietary fibre have been shown to decrease HbA1c, fasting glucose, fasting insulin, fructosamine, and HOMA-IR. However, the main underlying mechanism is still not fully understood, and the specific type and proportion of fibre supplementation to be recommended for such individuals is still controversial.
Currently, the available findings/ results from small RCTs are inconsistent. The systematic review method depends on combining data from many small studies in order a pooled estimate of the pooled effect. The purpose of this study is to conduct a systematic review and meta-analysis of randomized controlled trials (RCTs) assessing the effect of non-viscous fibre supplementation on fasting glucose and insulin in individuals with diabetes mellitus. We hope the findings of this study will play a role in developing the nutritional guidelines for individuals with diabetes mellitus.
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||514 participants|
|Official Title:||The Effect of Non-Viscous Fibre Supplementation on Glycemic Control in Individuals With Diabetes Mellitus: A Systematic Review & Meta-analysis of RCTs|
|Actual Study Start Date :||January 30, 2017|
|Actual Primary Completion Date :||June 30, 2017|
|Estimated Study Completion Date :||August 30, 2017|
- HbA1c [ Time Frame: ≥ 3 weeks ]Glycated Hemoglobin A1C
- FG [ Time Frame: ≥ 3 weeks ]Fasting Glucose
- FI [ Time Frame: ≥ 3 weeks ]Fasting Insulin
- Fructomsamine [ Time Frame: ≥ 3 weeks ]
- HOMA-IR [ Time Frame: ≥ 3 weeks ]Insulin Resistance
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03259724
|The Toronto 3D Knowledge Synthesis and Clinical Trials Unit, Clinical Nutrition and Risk Factor Modification Centre|
|Toronto, Ontario, Canada, M5C 2T2|