Effectiveness of Repetitive Transcranial Magnetic Stimulation in the Treatment of Chronic Neuropathic Pain (rTMS-CIC)
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|ClinicalTrials.gov Identifier: NCT03259451|
Recruitment Status : Withdrawn (No recruitment)
First Posted : August 23, 2017
Last Update Posted : April 12, 2018
|Condition or disease||Intervention/treatment|
|Chronic Neuropathic Pain||Device: Repetitive Transcranial Magnetic Stimulation (rTMS)|
Neuropathic pain is a public health problem because of its prevalence reaching nearly 7% of the general population and the effectiveness of current treatments often remains incomplete: only 30-40% of patients are relieved of 50% of their pain by a pharmacological approach.
As early as the 1990s, stimulation of the motor cortex by implanted electrodes made it possible to successfully treat certain chronic refractory neuropathic pain. In 1995 it was reported that the application of repeated shocks by transcranial magnetic stimulation of the motor cortex could induce an analgesic effect in a patient suffering from neuropathic pain.
This technique has proved its analgesic efficacy after an induction treatment over 5 days, in the context of chronic pain (neuropathic or fibromyalgia), but all the patients are not responders and there is currently, Of predictive criteria for response. It seems important to continue studies on this non-medicinal, non-invasive therapy with no significant adverse effects.
|Study Type :||Observational|
|Actual Enrollment :||0 participants|
|Official Title:||Effectiveness of Repetitive Transcranial Magnetic Stimulation in the Treatment of Chronic Neuropathic Pain: Retrospective Study on a Cohort of 149 Patients at Rennes University Hospital, From January 2014 to December 2015|
|Actual Study Start Date :||September 26, 2016|
|Actual Primary Completion Date :||December 31, 2017|
|Actual Study Completion Date :||December 31, 2017|
- Evaluation of the efficacy of rTMS in the treatment of chronic neuropathic pain in a short term [ Time Frame: Day 7 ]Improvement of pain symptoms by at least 30% on the numerical scale
- Evaluation of the efficacy of rTMS in the treatment of chronic neuropathic pain in a short term (≤ 1 month) [ Time Frame: Month 1 ]Improvement of pain symptoms by at least 30% on the numerical scale
- Evaluate the effectiveness of rTMS in the treatment of long-term chronic neuropathic pain (> 6 months) [ Time Frame: Month 6 ]Persistence of at least 30% improvement in pain symptoms on a numerical scale at the end of the sixth month (M6)
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03259451
|CHU de Rennes|
|Rennes, France, 35033|