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Successful Treatment of Maternal Listeria Monocytogenes Bacteremia in the First Trimester

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ClinicalTrials.gov Identifier: NCT03248973
Recruitment Status : Completed
First Posted : August 15, 2017
Last Update Posted : February 12, 2019
Sponsor:
Information provided by (Responsible Party):
Sheng-Mou Hsiao, Far Eastern Memorial Hospital

Brief Summary:
Successful Treatment of Maternal Listeria Monocytogenes Bacteremia in the First Trimester of Pregnancy

Condition or disease Intervention/treatment
Listeria Monocytogenes Drug: Ampicillin Injection

Detailed Description:
A 34-year-old nulliparous woman with 11 gestational weeks with flu-like illness was proved to be infection by Listeria monocytogenes, and then treated by intravenous ampicillin 2 g every 4 hours for 3 weeks. A healthy unaffected male baby was delivered at 41 weeks' gestation.

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Study Type : Observational
Actual Enrollment : 1 participants
Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Successful Treatment of Maternal Listeria Monocytogenes Bacteremia in the First Trimester of Pregnancy: a Case Report and Review of Literatures
Actual Study Start Date : April 3, 2017
Actual Primary Completion Date : January 8, 2018
Actual Study Completion Date : February 2, 2018

Resource links provided by the National Library of Medicine



Intervention Details:
  • Drug: Ampicillin Injection
    Ampicillin injection 2 g q4h for 3 weeks


Primary Outcome Measures :
  1. Successful treatment [ Time Frame: 1 month after delivery ]
    A favorable outcome of maternal listeria infection in the first trimester may be anticipated. Besides, intravenous ampicillin with or without gentamicin should be a reasonable treatment option for maternal listeria infection in the first trimester.



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Ages Eligible for Study:   20 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
One pregnant woman with listeria monocytogenes bacteremia in the first trimester
Criteria

Inclusion Criteria:

  • One pregnant woman with listeria monocytogenes bacteremia in the first trimester

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03248973


Locations
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Taiwan
Far Eastern Memorial Hospital
New Taipei, Taiwan, 220
Sponsors and Collaborators
Far Eastern Memorial Hospital

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Responsible Party: Sheng-Mou Hsiao, Chief, Department of Obstetrics & Gynecology, Far Eastern Memorial Hospital, Far Eastern Memorial Hospital
ClinicalTrials.gov Identifier: NCT03248973     History of Changes
Other Study ID Numbers: 106030-C
First Posted: August 15, 2017    Key Record Dates
Last Update Posted: February 12, 2019
Last Verified: February 2019

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Additional relevant MeSH terms:
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Bacteremia
Bacterial Infections
Sepsis
Infection
Systemic Inflammatory Response Syndrome
Inflammation
Pathologic Processes
Ampicillin
Anti-Bacterial Agents
Anti-Infective Agents