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Management of Non Convulsive Status Epilepticus

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT03245099
Recruitment Status : Unknown
Verified August 2017 by Rewaa Mohammed, Assiut University.
Recruitment status was:  Not yet recruiting
First Posted : August 10, 2017
Last Update Posted : August 10, 2017
Sponsor:
Information provided by (Responsible Party):
Rewaa Mohammed, Assiut University

Brief Summary:
Non convulsive status epilepticus is a persistent change in behavioural and or mental process from baseline associated with continuous epileptiform activity in electroencephalograph,it occur in about 50 percent in patients with coma and convulsions and in 8-13 percent in intensive care unit patients

Condition or disease Intervention/treatment
Status Epilepticus Other: cross sectional

Detailed Description:
Early recognition and treatment of non convulsive status epilepticus are essential to optimize response to treatment and to prevent neurological sequelae, over diagnosis and aggressive use of anticonvulsants can contribute to morbidity and mortality.It displays great diversity in response to anticonvulsants,therefore treatment in intensive care units is required for selected cases .The aetiology and clinical forms are strong predictors for the overall prognosis.Treatment is poorly understood and follows the standard regimen for convulsive status epilepticus

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Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Other
Time Perspective: Cross-Sectional
Official Title: Management of Non Convulsive Status Epilepticus
Estimated Study Start Date : December 2017
Estimated Primary Completion Date : December 2018
Estimated Study Completion Date : April 2019

Resource links provided by the National Library of Medicine



Intervention Details:
  • Other: cross sectional
    Electroencephalograph will be done to all patients who fulfill the inclusion criteria to detect presence of electrical discharge with in the brain.Complete blood count ,liver function test ,kidney function test ,blood glucose level and serum electrolytes will be done to selected cases according to the clinical presentation


Primary Outcome Measures :
  1. Number of cured patients [ Time Frame: An average of 1 year ]
    Number of cured patients



Information from the National Library of Medicine

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Ages Eligible for Study:   12 Months to 18 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
  • Patients 1-18 years
  • Generalized tonic clonic convulsions and prolonged post ictal period more than 30 minutes
  • Un explained coma ,stupor,confusion and psychic or speech disorder
Criteria

Inclusion Criteria:

  • patients who have generalized tonic colonic convulsions and prolonged post ictal state more than 30 minutes
  • patients presented with un explained psychic or speech disorder
  • patients presented with stupor or confusion
  • Patients presented with un explained coma

Exclusion Criteria:

  • patients with progressive neurological disease
  • Patients with severe cerebral anoxia
  • Patients with liver or hepatic impairment

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03245099


Contacts
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Contact: Gamal Askar, MD 01111686162 Gamal.askar@med.au.edu.eg
Contact: Eman Fathallah, MD 01115191158 Mean.mohamed@med.au.edu.eg

Locations
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Egypt
AssiutU
Assiut, Egypt
Contact: Rewaa         
Sponsors and Collaborators
Assiut University
Investigators
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Principal Investigator: Rewaa Mohammed, MD Assiut University

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Responsible Party: Rewaa Mohammed, Principlal investigator, Assiut University
ClinicalTrials.gov Identifier: NCT03245099    
Other Study ID Numbers: MONCSE
First Posted: August 10, 2017    Key Record Dates
Last Update Posted: August 10, 2017
Last Verified: August 2017
Additional relevant MeSH terms:
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Status Epilepticus
Seizures
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms