EXPert System, ALImentary (EXPALI)
|ClinicalTrials.gov Identifier: NCT03208699|
Recruitment Status : Completed
First Posted : July 5, 2017
Last Update Posted : July 6, 2017
Eating disorders (ED) are often undetected in the general population resulting in delayed treatment. The SCOFF questionnaire has been validated for eating disorders screening in primary care, but does not identify the type of eating disorder.
Objective: Investigators evaluated the performance of a clinical algorithm (ExpaliTM) combining answers to SCOFF questionnaire with Body Mass Index (BMI) to identify four Broad Categories of ED derived from DSM-5.
Design: Clinical algorithm (ExpaliTM) was developped from 104 combinations of BMI levels and answers to five SCOFF questions. Two senior ED specialists allocated each combination to one of the four Broad Categories of ED (DSM-5 diagnostics): restrictive disorder (anorexia nervosa typical, atypical and restrictive food intake disorders), bulimic disorder (typical and with low frequency or duration), hyperphagic disorder (binge eating disorders typical and with low frequency or duration) and other specified ED. The performance of ExpaliTM was evaluated on data from patients referred to the Nutrition Department including a precise DSM-5 diagnosis of ED, a positive SCOFF test (at least 2 "yes" answers) and BMI. Sensitivity, specificity values with a 95% confidence interval (95% CI) and Youden index were calculated for each category.
|Condition or disease|
|Eating Disorder Symptom|
|Study Type :||Observational|
|Actual Enrollment :||256 participants|
|Official Title:||Screening and Diagnosis Help of Eating Disorders|
|Actual Study Start Date :||October 1, 2015|
|Actual Primary Completion Date :||October 1, 2015|
|Actual Study Completion Date :||December 31, 2015|
- Sensivity and specificity of the clinical algorithm [ Time Frame: inclusion ]