The Effect of Popliteal Plexus Block on Pain After Total Knee Arthroplasty
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|ClinicalTrials.gov Identifier: NCT03198403|
Recruitment Status : Completed
First Posted : June 26, 2017
Last Update Posted : September 29, 2017
|Condition or disease||Intervention/treatment||Phase|
|Popliteal Plexus Block Total Knee Arthroplasty||Drug: Bupivacaine-epinephrine||Phase 4|
Cadaver dissection studies have shown a spread of dye to the popliteal fossa and colored the popliteal plexus by injecting in the distal part of the adductor Canal.
The popliteal plexus is formed by contribution from the tibial and the obturator nerves.
Investigators hypothesized that a PPB may reduce postoperative pain after total knee arthroplasty.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||17 participants|
|Intervention Model:||Parallel Assignment|
|Intervention Model Description:||Pilot Study|
|Masking:||None (Open Label)|
|Official Title:||The Effect of Popliteal Plexus Block on Postoperative Pain After Total Knee Arthroplasty|
|Actual Study Start Date :||August 1, 2017|
|Actual Primary Completion Date :||September 26, 2017|
|Actual Study Completion Date :||September 28, 2017|
Experimental: Popliteal plexus block
Patients with an FTB, reporting postoperative pain (NRS > 3) will have a popliteal plexus block
Popliteal plexus block with 10 mL of bupivacaine-epinephrine 5 mg/mL + 5 microgram/mL.
No Intervention: No intervention
Patients with postoperative pain NRS < or = 3
- The percentage of patients with postoperative pain NRS [ Time Frame: 0 - 60 minutes ]Evaluated as the percentage of patients with postoperative pain NRS >3, dropping in pain score to NRS = or < 3 after the PPB
- Percentage of patients having a femoral triangle block(FTB) reporting NRS > 3 [ Time Frame: Pain scores every 15 minutes (from end injection FTB to NRS>3 or 3 hours after full sensation of the leg) ]Percentage of patients having a FTB, reporting postoperative pain NRS >3
- Onset time of PPB [ Time Frame: NRS every 5 minutes after PPB (From 0 - 60 minutes after PPB) ]Time from end of injection of PPB to NRS = or < 3
- Turn off time of spinal anesthesia [ Time Frame: Time from arrival in PACU and during maximum 6 hours ]Time from arrival in PACU to normal cutaneous sensation (measured by a neuro-pen, sensation=point 2) on the lateral part of the thigh and lateral part of the lower leg
- Correlation between normal cutaneous sensation and developing of pain [ Time Frame: From arrival in PACU and during maximum 6 hours ]Correlation between normal cutaneous sensation (measured by a neuro-pen, sensation=point 2) and developing of pain (NRS>3)
- The effect of the PPB on cutaneous sensation [ Time Frame: NRS every 5 minutes after PPB (From 0 - 60 minutes after PPB) ]Tested on the lateral part of the lower leg
- The effect of the PPB on muscle strength of the foot [ Time Frame: Baseline and 1 hour after PPB ]Dorsal flexion and plantar flexion in the ankle joint, measured with a handheld dynamometer
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03198403
|Silkeborg, Denmark, 8600|
|Principal Investigator:||Charlotte Runge, MD||University of Aarhus|