Risk Factors of Delirium in Sequential Sedation Patients in Intensive Care Unit
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03194360|
Recruitment Status : Completed
First Posted : June 21, 2017
Last Update Posted : June 21, 2017
|Condition or disease|
|Delirium Mechanical Ventilation Sedation|
Previous studies have showed that patients under mechanical ventilation have a higher risk for experiencing delirium than nonmechanically ventilated patients (20%-50%). Its occurrence is also more frequent in elder patients. More than that, it is often hard to identify delirium by physicians, leading to unreasonable management of ICU patients.
And delirium is one of main adverse events in ventilated patients who receive long-term usage of mono-sedative. Sequential sedation may reduce these adverse effects.
However, few present studies focus on delirium in sequential sedation patients. Thus, in this study, we aimed to determine the factors of delirium in patients who received sequential sedation in ICU.
|Study Type :||Observational|
|Actual Enrollment :||141 participants|
|Official Title:||Risk Factors of Delirium in Sequential Sedation Patients in Intensive Care Unit|
|Actual Study Start Date :||December 1, 2015|
|Actual Primary Completion Date :||January 15, 2017|
|Actual Study Completion Date :||January 15, 2017|
- Delirium assessment in Sequential Sedation Patients [ Time Frame: A maximum of twenty-eight days or until ICU discharge, whichever occurred first. ]The primary outcome of this study was delirium. Patient evaluations were implemented using Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) scale every four hours a day for a maximum of twenty-eight days or until ICU discharge, whichever occurred first. The risk factors were analyzed using risk regression (logistic-regression). Any variables which had P<0.2 after univariable logistic-regression or potential variables associated with delirium were included for multivariable logistic-regression. P<0.05 was considered to represent statistical significance.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03194360
|Department of Critical care medicine of West China Hospital|
|Chengdu, Sichuan, China, 610041|