Radiographic Assessment of Glass Ionomer Restorations With and Without Prior Application of Nano Silver Fluoride in Occlusal Carious Molars Treated With Partial Caries Removal Technique
|ClinicalTrials.gov Identifier: NCT03193606|
Recruitment Status : Completed
First Posted : June 21, 2017
Last Update Posted : May 3, 2019
eligible teeth will be randomly divided into two groups to be treated with incomplete caries excavation (A), where (A1) represents teeth to be treated with application of Nano silver fluoride solution on remaining carious dentin prior to final permanent glass ionomer restoration application, (A2) represents comparator group to be restored without Nano silver fluoride application prior to restoration. Every participant will receive both the intervention and control treatment. Image of radiographic density of remaining carious dentin will be evaluated using PSP plate at baseline immediately after restoration and after 6 months after restorative procedures.
The null hypothesis tested is that application of Nano silver fluoride solution prior to glass ionomer restoration will not increase radiopacity of the underlying dentin treated by incomplete carious removal technique compared to that of direct glass ionomer restoration without prior application of Nano silver fluoride.
|Condition or disease||Intervention/treatment||Phase|
|Partial Dentin Caries Removal||Other: nano silver fluoride solution||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||22 participants|
|Intervention Model:||Parallel Assignment|
|Intervention Model Description:||split mouth randomized clinical trial|
|Masking:||Double (Participant, Outcomes Assessor)|
|Official Title:||Radiographic Assessment of Glass Ionomer Restorations With and Without Prior Application of Nano Silver Fluoride in Occlusal Carious Molars Treated With Partial Caries Removal Technique (Randomized Clinical Trial)|
|Actual Study Start Date :||July 3, 2018|
|Actual Primary Completion Date :||February 28, 2019|
|Actual Study Completion Date :||March 1, 2019|
Experimental: nano silver fluoride solution
carious dentin to be treated with partial caries excavation with application of nano silver fluoride solution prior to glass ionomer restoration.
Other: nano silver fluoride solution
prepared Nano-silver fluoride could have the capability to arrest caries. As its Nano silver particles have an antimicrobial activity against Mutans Streptococci and Lactobacilli; the main pathogens involved in the development of carious lesions. In addition, its fluoride component is well known to enhance remineralization and inhibit bacterial activity. So, Nano silver fluoride could be a promising solution to combat residual bacteria in tooth cavity with effective remineralization potential on remaining carious dentin
No Intervention: no nano silver fluoride
carious dentin to be treated with partial caries excavation without application of nano silver fluoride solution restored directly with glass ionomer.
- Caries remineralization. (Mineral density) [ Time Frame: six months ]using Density measurement tool in the Digora software
- dentin bridge formation. [ Time Frame: six months ]Linear measurement tool in the Digora software in Mm
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03193606
|Giza, Egypt, 002|
|Study Director:||Heba Ah El deeb||Associate professor, Conservative dentistry department Cairo University|