Carbon Dioxide Laser and Cryotherapy in Treatment of Warts
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|ClinicalTrials.gov Identifier: NCT03166137|
Recruitment Status : Unknown
Verified May 2017 by Kadija Yousef Badawy, Assiut University.
Recruitment status was: Not yet recruiting
First Posted : May 25, 2017
Last Update Posted : May 25, 2017
|Condition or disease||Intervention/treatment||Phase|
|Common Warts||Device: Carbon dioxide laser Device: Cryotherapy||Not Applicable|
A range of types of wart have been identified, varying in shape and site affected, as well as the type of human papillomavirus involved.
- Common wart (Verruca vulgaris).
- Flat wart (Verruca plana).
- Filiform or digitate wart.
- Genital wart (venereal wart, Condyloma acuminatum, Verruca acuminata).
- Mosaic wart.
- Periungual wart.
- Plantar wart (verruca, Verruca plantaris). Despite the presence of several therapeutic options, treatment of warts can present a challenge and they are not uniformly effective. Viral warts often disappear without treatment. In case of pain, discomfort and long duration they can be treated . Treatment options include cryotherapy, electrocautery, salicylic acid, immune therapy, minor surgery or laser surgery.
Common warts have a distinctive appearance and can usually be diagnosed with the unaided eye; however, early growth stages and post-treatment warts are less easily diagnosed. Published dermoscopic features of common warts include frogspawn pattern, mosaic pattern and dotted, linear, globular or coiled vessels. Mosaic pattern consists of relatively flattened, rounded structures of similar size, resembling a jigsaw puzzle. Frogspawn pattern consists of densely packed papillae, each containing red dot or loop, surrounded by a whitish halo. Vascular structures seen dermoscopically in common warts as red or black dotted, linear, globular and coiled vessels. Haemorrhages are possible additional features, with black dots corresponding to thrombosed vessels. Hairpin vessels were usually seen in non-wart lesions.
In this study, we aim to compare two therapeutic modalities, the clinical effectiveness and safety of carbon dioxide laser and cryotherapy in the treatment of viral warts together with dermoscopic evaluation of viral warts before and after treatment.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||60 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Comparative Evaluation of Carbon Dioxide Laser and Cryotherapy by Dermoscopy in Treatment of Viral Wart|
|Estimated Study Start Date :||August 1, 2017|
|Estimated Primary Completion Date :||August 1, 2018|
|Estimated Study Completion Date :||August 1, 2019|
Experimental: Carbon dioxide laser group
(group A): thirty patients will be treated by application of carbon dioxide laser.
Device: Carbon dioxide laser
Radiation by carbon dioxide laser
Active Comparator: Cryotherapy group
(group B): thirty patients will be treated by cryotherapy application.
Device using cooling effect
- Number and size of the lesions. [ Time Frame: Two months ]Dermoscopic evaluation
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03166137
|Contact: Nagwa Essa, PDfirstname.lastname@example.org|
|Contact: Hanan Ahmed, MDemail@example.com|