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Quantitative Evaluation of Bitter Taste in Obesity

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ClinicalTrials.gov Identifier: NCT03149666
Recruitment Status : Completed
First Posted : May 11, 2017
Last Update Posted : May 11, 2017
Sponsor:
Information provided by (Responsible Party):
Julio Sergio Marchini, University of Sao Paulo

Brief Summary:

Although taste influences food choices and favours diseases like obesity, there is no consensus about the existence of correlations between bitterness and anthropometric variables. Also, an electronic-based method for data collection could provide a more appropriate way for the evaluation of taste perception and save time.

The objective is to search for correlations between bitterness and anthropometric variables.


Condition or disease
Obesity

Detailed Description:
A cross-sectional study evaluating correlations between the bitterness rates given on a generalized Labeled Magnitude Scale, anthropometrics and other variables. Bitterness perceptions at the tip of the tongue (TOTp) and at the whole mouth (WMp) were recorded using a locally developed novel cloud-based software (Cloud-gLMS). The ANCOVA test was adjusted using TOTp and WMp as dependent variables and age, height, weight, BMI, gender, waist circumference, alcohol intake, comorbidities, and use of medications as independent variables.

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Study Type : Observational
Actual Enrollment : 262 participants
Observational Model: Other
Time Perspective: Cross-Sectional
Official Title: Anthropometric Variables and Perception of Bitter Taste in Obese Adults or Not
Actual Study Start Date : February 1, 2015
Actual Primary Completion Date : January 31, 2016
Actual Study Completion Date : July 1, 2016

Resource links provided by the National Library of Medicine


Group/Cohort
Evaluation of bitter taste
Participants will be evaluated as to the intensity of bitter taste when performing watery mouthwash with quinine.



Primary Outcome Measures :
  1. Sensitivity of bitter taste 1 [ Time Frame: 1 time ]
    It will be gently applied at the end of the tongue, by means of a swab soaked in the quinine solution at room temperature, in continuous movements from left to right, and will point a note to the bitter level.

  2. Sensitivity of bitter taste 2 [ Time Frame: 1 time ]
    The volunteer will perform a "mouthwash" with the quinine solution, and will point a note to the bitter level.



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Ages Eligible for Study:   18 Years to 59 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Healthy people without obesity and people with obesity.
Criteria

Inclusion Criteria:

  • Weight limit of 150 kg and who are able to read the text with the guidelines on how to be punctuated the sensation of bitter in the generalized labeled scale.

Exclusion Criteria:

  • Being a relative of the first degree of a patient already included in the research, tobacco in the forms of cigarettes, pipes and cigars in the last 30 days, presence of coryza, nasal congestion or frequent sneezing, dental treatment on the same day of the research. Being a dementia sufferer, having an altered, drowsy level of consciousness. Show upper limb tremor visible.

Publications:
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Responsible Party: Julio Sergio Marchini, Principal Investigator, University of Sao Paulo
ClinicalTrials.gov Identifier: NCT03149666     History of Changes
Other Study ID Numbers: HCRP 924/2015
First Posted: May 11, 2017    Key Record Dates
Last Update Posted: May 11, 2017
Last Verified: May 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Additional relevant MeSH terms:
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Obesity
Overnutrition
Nutrition Disorders
Overweight
Body Weight
Signs and Symptoms