Predictive Role of Red Cell Distribution Width in Upper GI Bleeding Patients
|ClinicalTrials.gov Identifier: NCT03119987|
Recruitment Status : Completed
First Posted : April 19, 2017
Last Update Posted : March 7, 2018
|Condition or disease||Intervention/treatment|
|Gastrointestinal Hemorrhage||Diagnostic Test: Red cell distribution widths|
This is a retrospective clinical study including the UGI patients in ED. All data will be collected through the electrical medical records. The major endpoints are the high risk patients and 30-days mortality which defined cases of including any of one among the death, re-bleeding, and received the intervention (such as blood transfusion, endoscopic therapy and operation).
Investigators assessed the relationship between initial RDW level and high risk patients and 30-days mortality. In addition, investigators compare the dicrimination power for predicting outcomes between the UGIB scoring system and RDW level.
Univariate and multivariate logistic regression testing and a Cox hazard regression model were used to determine the factors associated with outcome variables. In addition, investigators constructed receiver operating characteristic curves, and the areas under the curves and confidence intervals were calculated to compare the discriminatory power for outcomes.
|Study Type :||Observational|
|Actual Enrollment :||400 participants|
|Official Title:||Efficacy of Red Cell Distribution Width as a Predictor of High Risk and Early Mortality in Upper Gastro-intestinal Bleeding|
|Actual Study Start Date :||January 1, 2011|
|Actual Primary Completion Date :||December 30, 2012|
|Actual Study Completion Date :||December 30, 2014|
Those who was diagnosed as UGI bleeding at emergency department during the study periods. Red cell distribution widths wers checked at all patients.
Diagnostic Test: Red cell distribution widths
Measured value of Red cell distribution widths in initial laboratory result of blood cell counts at emergency department
- High risk [ Time Frame: 30 days ]Case of the death or re-bleeding, or blood transfusion or endoscopic therapy or operation.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03119987
|Principal Investigator:||Sang O Park, MD||Department of Emergency Medicine, Konkuk University School of medicine|