Working…
COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC: https://www.coronavirus.gov.

Get the latest research information from NIH: https://www.nih.gov/coronavirus.
ClinicalTrials.gov
ClinicalTrials.gov Menu

Effect of Inferior Alveolar and Gow-Gates Nerve Block Techniques for Symptomatic Mandibular Molars

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT03117491
Recruitment Status : Completed
First Posted : April 18, 2017
Last Update Posted : May 9, 2017
Sponsor:
Information provided by (Responsible Party):
Masoud Saatchi, DDS MSc, Isfahan University of Medical Sciences

Brief Summary:
Introduction: to evaluate the efficacy of inferior alveolar nerve block (IANB), Gow-Gates nerve block (GGNB), and their combination in patients with irreversible pulpitis. Methods: One hundred fifty subjects with irreversible pulpitis of a mandibular molar were selected. subjects randomly received two IANB injections or two GGNB injections or their combination of 1.8 mL 2% lidocaine with 1:100,000 epinephrine. Success was specified as no or mild pain on the basis of Heft-Parker visual analogue scale recordings up on the access cavity preparation or initial instrumentation. Data were analyzed by Kruskal-Wallis, and ANOVA tests.

Condition or disease Intervention/treatment Phase
Symptomatic Irreversible Pulpitis Procedure: GGNB injections Procedure: IANB injections Procedure: GGNB + IANB injections Phase 3

Detailed Description:
Introduction: to evaluate the efficacy of inferior alveolar nerve block (IANB), Gow-Gates nerve block (GGNB), and their combination in patients with irreversible pulpitis. Methods: One hundred fifty subjects with irreversible pulpitis of a mandibular molar were selected. subjects randomly received two IANB injections or two GGNB injections or their combination of 1.8 mL 2% lidocaine with 1:100,000 epinephrine. Success was specified as no or mild pain on the basis of Heft-Parker visual analogue scale recordings up on the access cavity preparation or initial instrumentation. Data were analyzed by Kruskal-Wallis, and ANOVA tests.

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 150 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Other
Official Title: Effect of Inferior Alveolar and Gow-Gates Nerve Block Techniques for Symptomatic Mandibular Molars
Actual Study Start Date : December 1, 2015
Actual Primary Completion Date : November 1, 2016
Actual Study Completion Date : December 1, 2016

Arm Intervention/treatment
Active Comparator: GGNB injection technique
In GGNB group, every patient received two1.8-mL cartridges of 2% lidocaine with 1:80,000 epinephrine using the GGNB technique
Procedure: GGNB injections
The patients received two GGNB injections of 1.8 mL 2% lidocaine with 1:100,000 epinephrine

Active Comparator: IANB injection technique
In IANB group, every patient received two 1.8-mL cartridges of 2% lidocaine with 1:80,000 epinephrine using the IANB technique
Procedure: IANB injections
The patients received two IANB injections of 1.8 mL 2% lidocaine with 1:100,000 epinephrine

Active Comparator: GGNB + IANB injection technique
In IANB + GGNB group, every patient received one 1.8-mL cartridges of 2% lidocaine with 1:80,000 epinephrine using the IANB technique and one 1.8-mL cartridges of 2% lidocaine with 1:80,000 epinephrine using the GGNB technique
Procedure: GGNB + IANB injections
The patients received one GGNB injection plus one IANB injection of 1.8 mL 2% lidocaine with 1:100,000 epinephrine




Primary Outcome Measures :
  1. the success rate of GGNB local anesthesia technique based on Heft-Parker visual analog scale [ Time Frame: at time of access cavity preparation ]
  2. the success rate of IANB local anesthesia technique based on Heft-Parker visual analog scale [ Time Frame: at time of access cavity preparation ]
  3. the success rate of GGNB + IANB local anesthesia techniques based on Heft-Parker visual analog scale [ Time Frame: at time of access cavity preparation ]

Secondary Outcome Measures :
  1. initial pain based on Heft-Parker visual analog scale [ Time Frame: before treatment ]


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • vital mandibular molar tooth
  • diagnosis of symptomatic irreversible pulpitis

Exclusion Criteria:

  • younger than 18 years old
  • history of significant medical conditions
  • allergies to local anesthetics or sulfites
  • pregnancy
  • taking any medications that might influence anesthetic assessment
  • active sites of pathosis in area of injection
  • inability to give informed consent

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03117491


Locations
Layout table for location information
Iran, Islamic Republic of
Isfahan University of Medical Sciences
Isfahan, Iran, Islamic Republic of
Sponsors and Collaborators
Isfahan University of Medical Sciences
Layout table for additonal information
Responsible Party: Masoud Saatchi, DDS MSc, Professor of Endodontics, Isfahan University of Medical Sciences
ClinicalTrials.gov Identifier: NCT03117491    
Other Study ID Numbers: 395437
First Posted: April 18, 2017    Key Record Dates
Last Update Posted: May 9, 2017
Last Verified: April 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No
Keywords provided by Masoud Saatchi, DDS MSc, Isfahan University of Medical Sciences:
Gow-Gates nerve block
Inferior alveolar nerve block
local anesthesia
molar
pulpitis
Additional relevant MeSH terms:
Layout table for MeSH terms
Pulpitis
Dental Pulp Diseases
Tooth Diseases
Stomatognathic Diseases