Strongest Predictors of a Positive Outcome After Physiotherapy for Knee Osteoarthritis
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|ClinicalTrials.gov Identifier: NCT03113149|
Recruitment Status : Terminated (Recruitment too slow, probably due to the procedure considered too complicated.)
First Posted : April 13, 2017
Last Update Posted : November 24, 2017
Individuals with painful knee osteoarthritis (OA) experience restricted physical function. Few previous studies have investigated comprehensive sets of constructs and tests to investigate physical function in these patients. Most single studies of knee OA patients show limited scope for explaining physical function in the perspective of WHO's International Classification of Functioning, Disability and Health (ICF) 3 levels: Body functions (the bodily level), Activities (individual level), and Participation (societal level). On the bodily level there is limited case-control knowledge on muscle strength beyond the knee and endurance-strength in general. On the activity level, there is similar limitation of biomechanical bodily features in stair climbing. On the participation level the situation is similar for objective performance. Measures are needed that inter-relate all three levels of ICF. These should also include well discriminating tests e.g. knee strength, walking, and activities of daily life (ADL), as well as both objective and subjective measures.
The purpose of this study is to explore mechanisms that can explain physical function in patients with knee OA in primary care. The study's main and primary goal is to quantify which baseline factors and change scores are the strongest predictors of a positive treatment outcome in terms of patients' global perceived change after physiotherapy. Secondary research question is: which factors are the strongest predictors of a positive outcome of physiotherapy in knee OA, in terms of pain intensity, patient specific functional scale, and function in daily living?
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||3 participants|
|Official Title:||Which Factors Are the Strongest Predictors of a Positive Outcome After Physiotherapy for Patients With Knee Osteoarthritis?|
|Actual Study Start Date :||May 1, 2017|
|Actual Primary Completion Date :||August 31, 2017|
|Actual Study Completion Date :||August 31, 2017|
Patients with knee osteoarthritis after having started physical therapy
- patient global perceived effect [ Time Frame: Change from baseline 'patient global perceived effect' at 3 months ]patient global perceived effect scale (Dworkin 2005, Evans 2014)
- Patient Specific Functional Scale [ Time Frame: Change from baseline 'Patient Specific Functional Scale' at 3 months ]Patient Specific Functional Scale (Stratford, 1995)
- Pain intensity [ Time Frame: Change from baseline 'Pain intensity' at 3 months ]Pain Intensity scale (Dworkin 2005)
- Function of daily living [ Time Frame: Change from baseline 'Function of daily living' at 3 months ]Function of daily living scale (KOOS) (Roos & Lohmander 2003)
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03113149
|Department of Neuromedicine and Movement Science, NTNU|
|Study Director:||Jorunn Helbostad, prof||Norwegian University of Science and Technology|