The Association Between Nephrolithiasis and Periodontal Status
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|ClinicalTrials.gov Identifier: NCT03102086|
Recruitment Status : Unknown
Verified March 2018 by machtei, Rambam Health Care Campus.
Recruitment status was: Recruiting
First Posted : April 5, 2017
Last Update Posted : May 16, 2018
Dental calculus is a calcified deposits firmly attached to teeth and implants surfaces. Dental calculus is strongly associated with periodontitis and considered to have indirect role in the pathogenesis of periodontal diseases. Dental calculus composed primarily of calcium phosphate mineral salts originated in the saliva covered by unmineralized bacterial layer. Composition of calculus varies from person to person and influenced by numerous variables such as: age, gender systemic disease and ethnic background.
Nephrolithiasis (kidney stones) are composed of insoluble salts of constituents of the forming urine. The most two frequent stone types are: Calcium oxalate (with a frequency of 15% -35%) and Calcium phosphate (5% -20%). The prevalence of kidney stones varies with race, sex, and geographic location. In the United States for men, kidney stone rates vary between 4%-9%, and for women, kidney stone rates range between 2%-4%.
Previous studies dealt with the connection between sialolithiasis and nephrolithiasis were inconclusive. To the authors' best knowledge no studies were done to examine the associations between nephrolithiasis and dental calculus. Thus, the aim of this study is to compare the mineral composition of both dental calculus and nephrolithiasis and determine whether nephrolithiasis composition may be linked to the periodontal status.
|Condition or disease||Intervention/treatment|
|Periodontal Diseases Nephrolithiasis||Procedure: Scaling|
|Study Type :||Observational|
|Estimated Enrollment :||20 participants|
|Official Title:||The Association Between Nephrolithiasis and Periodontal Status|
|Actual Study Start Date :||May 11, 2017|
|Estimated Primary Completion Date :||December 2018|
|Estimated Study Completion Date :||January 2019|
- Procedure: Scaling
Scaling of dental calculus
- the composition of both specimens [ Time Frame: the analysis will take 9 months ]The X-ray diffraction of both kidney stone and dental calculus will result in the composition of the two, and comparison will be done
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03102086
|Rambam Health Care Campus, Dept. of Periodontology||Recruiting|
|Haifa, Israel, 31096|
|Contact: prof. Eli Machtei, DMD 9720545503199 email@example.com|