Evaluation of Root Coverage by Connective Graft and Different Root Conditioning Methods
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|ClinicalTrials.gov Identifier: NCT03095378|
Recruitment Status : Completed
First Posted : March 29, 2017
Last Update Posted : March 29, 2017
|Condition or disease||Intervention/treatment||Phase|
|Gingival Recession||Procedure: Control Procedure: citric acid plus tetracycline Procedure: antimicrobial photodynamic therapy||Not Applicable|
Citric acid plus tetracycline has properties of root surface decontamination, surface demineralization and exposure of collagen fibers.
Antimicrobial photodynamic therapy has been widely used in Periodontics to obtain reduction of periodontopathogenic bacteria with absence of systemic side effects and minimal bacterial resistance. Also, it has properties of root demineralization and exposure of collagen fibers. These properties may enhance root coverage in procedures of subepithelial connective graft.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||14 participants|
|Intervention Model:||Parallel Assignment|
|Intervention Model Description:||Interventions in different patients|
|Masking:||Single (Outcomes Assessor)|
|Masking Description:||The outcome assessor did not have access to patient's records|
|Official Title:||Evaluation of Root Coverage by Subepithelial Connective Graft Associated to Root Conditioning by Citric Acid Plus Tetracycline and Antimicrobial Photodynamic Therapy: A Randomized Clinical Trial|
|Actual Study Start Date :||March 10, 2014|
|Actual Primary Completion Date :||February 10, 2017|
|Actual Study Completion Date :||March 10, 2017|
Active Comparator: Control
Root treatment with scaling and root planing.
Periodontal plastic surgery aiming root coverage by palatal connective tissue graft. Root treatment with scaling and root planing
Experimental: Citric acid plus tetracycline
Root treatment with 50% citric acid plus 10% tetracycline, pH1, passive application for 90s.
Procedure: citric acid plus tetracycline
Periodontal plastic surgery aiming root coverage by palatal connective tissue graft. Root treatment with citric acid plus tetracycline
Experimental: Antimicrobial photodynamic therapy
Antimicrobial photodynamic therapy with toluidine blue O (100ug/ml - 60s pre-irradiation - pH4) and red laser (660nm, 30 milliwatts, 45 joules per square centimeter, sweeping mode, 90s)
Procedure: antimicrobial photodynamic therapy
Periodontal plastic surgery aiming root coverage by palatal connective tissue graft. Root treatment with antimicrobial photodynamic therapy
- Total root coverage measured with a periodontal probe in mm [ Time Frame: one year ]Distance from cemento-enamel junction to gingival margin = 0 mm
- Keratinized mucosa width measured with a periodontal probe in mm [ Time Frame: one year ]Ideal if keratinized mucosa width > 5mm
- Dentin hypersensitivity measured by applying an air jet on teeth and patient fills up a visual analogue scale [ Time Frame: one year ]Ideal if scale = 0
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03095378
|Bauru School of Dentistry|
|Bauru, Sao Paulo, Brazil, 17012-901|