Effects of Exercise and Nicotine on Cognition in Smokers
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|ClinicalTrials.gov Identifier: NCT03091699|
Recruitment Status : Unknown
Verified May 2017 by Dr. Harry Prapavessis, Western University, Canada.
Recruitment status was: Recruiting
First Posted : March 27, 2017
Last Update Posted : May 12, 2017
|Condition or disease||Intervention/treatment||Phase|
|Smoking Cessation||Drug: Nicotine Behavioral: Moderate Intensity Exercise||Phase 3|
Show Detailed Description
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||34 participants|
|Intervention Model:||Sequential Assignment|
|Intervention Model Description:||Sequential two stage trial. Stage 1 will utilize a within-counterbalanced approach while stage 2 will utilize a randomized trial.|
|Masking:||None (Open Label)|
|Official Title:||The Acute Effects of Moderate Intensity Exercise and Nicotine on Cognition in Smokers|
|Actual Study Start Date :||May 1, 2017|
|Estimated Primary Completion Date :||April 2018|
|Estimated Study Completion Date :||April 2018|
Experimental: Moderate intensity exercise
The Exercise intervention will persist of a 20-minute bout of moderate intensity aerobic exercise which by definition is 40-65% of Maximum Heart Rate. Exercise consisted of a 2-minute warm-up, followed by 15 min of walking at a rate, which will allow you to reach 2/3 of your max heart rate, and then a 3-minute cool down on a treadmill equaling 20 minutes. Heart Rate will be examined with Polar Wearlink coded Heart Rate monitors to attain the specific exercise intensity.
Behavioral: Moderate Intensity Exercise
Participants will be required to perform 20 minutes of acute moderate intensity exercise (brisk walk) on a treadmill.
Active Comparator: Nicotine Inhalation
The nicotine inhalation group will smoke a cigarette to completion of their choice, in the 20 minute time period allocated in the Exercise and Health Psychology Lab psychological assessment room (the room will be equipped with windows that allow for ventilation and an air purifier. During this time the participant will refrain from conversation.
Participants will be required to smoke a cigarette to completion in a 20 minute time frame.
Other Name: Cigarettes
- Cognition (working memory) accuracy [ Time Frame: 1 day ]intervention effects on the 3-back task accuracy (percentage of correct responses)
- Cognition (working memory) reaction time [ Time Frame: 1 day ]intervention effects on the 3-back task reaction time (milliseconds)
- Cognition (working memory) accuracy [ Time Frame: 1 day ]intervention effects on the 0,1,2-back task and accuracy (percentage of correct responses)
- Cognition (working memory) reaction time [ Time Frame: 1 day ]intervention effects on the 0,1,2-back task and accuracy (percentage of correct responses)
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03091699
|Contact: Harry Prapavessis, PhD||5196612111 ext email@example.com|
|London, Ontario, Canada, N6G 1G9|
|Contact: Harry Prapavessis, PhD 5196612111 ext 80173 firstname.lastname@example.org|
|Principal Investigator: Harry Prapavessis, PhD|
|Sub-Investigator: Matthew Fagan, B.A.|
|Principal Investigator:||Harry Prapavessis, PhD||Professor|