Guided Imagery Training and Self-Referential Processing
|ClinicalTrials.gov Identifier: NCT03056963|
Recruitment Status : Completed
First Posted : February 17, 2017
Last Update Posted : July 19, 2017
The purpose of this study is to examine the efficacy of a guided imagery paradigm for reducing negative ways of thinking about the self. There will be at least 60 participants enrolled at the University of Texas at Austin. Participants will be randomly selected to receive one of two types of trainings, each over the course of two weeks. Participants will undergo the training exercises at home. The training exercises will help them to think differently about themselves.
Participants will be able to determine if they are eligible, and then participate, by filling out a screening questionnaire online.
|Condition or disease||Intervention/treatment||Phase|
|Depression Negative Thoughts||Behavioral: Positive Self-Reference Training Behavioral: Neutral Training Control||Not Applicable|
This study uses a randomized controlled trial to compare two types of guided imagery. One intervention is an active intervention; the other is intended to be inert. These interventions were developed based on extensive research indicating the efficacy of using imagery in depression, and a perceived lack of treatments targeting biased self-referential processing.
This protocol aims to develop a novel intervention which can be used on its own or as an adjunct to existing treatments. Common treatments for Major Depressive Disorder (MDD) are diffuse; this paradigm instead aims to specifically target negative self-schema, a part of the cognitive model of MDD. This study focuses on participants with elevated depressive symptoms.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||86 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Guided Imagery Training and Self-Referential Processing|
|Actual Study Start Date :||March 17, 2017|
|Actual Primary Completion Date :||June 19, 2017|
|Actual Study Completion Date :||June 19, 2017|
Experimental: Positive Self-Reference Training
Participants in this arm will complete the Positive Self-Reference Training (PSRT).
Behavioral: Positive Self-Reference Training
Participants in this intervention will review a brief psychoeducational video describing the training, and then be given cues every other day designed to practice skills. Participants will then practice visualizing and describing scenes based on these cues. This training will be focused on positive self-referent material.
Placebo Comparator: Neutral Training Control
Participants in this arm will complete the neutral training paradigm.
Behavioral: Neutral Training Control
Participants in this intervention will review a brief psychoeducational video describing the training, and then be given cues every other day designed to practice skills. Participants will then practice visualizing and describing scenes based on these cues. This training will be focused on neutral, non-self-referent material.
- Change in response on the Self-Referent Encoding Task (SRET) [ Time Frame: Participants will complete the SRET at baseline, after one week, and after two weeks. Change will be assessed primarily as SRET at two weeks MINUS SRET at baseline. ]The SRET is a task that asks participants to categorize words as self-referential or not. Its outcomes are focused on behavioral response and reaction time. We have shown that it has good test-retest reliability over the course of one week.
- Depressive Symptomatology [ Time Frame: Participants will complete measures of depressive symptoms at baseline, after one week, and after two weeks. ]Measures of depressive symptoms will be measured with the CESD, a self-report questionnaire used in the literature to measure levels of depression. This questionnaire has good test-retest reliability, and reliably changes with symptoms.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03056963
|United States, Texas|
|University of Texas at Austin|
|Austin, Texas, United States, 78703|
|Principal Investigator:||Justin Dainer-Best||University of Texas at Austin|