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The Effect of a Citrus Extract on Exercise Performance in Moderately Trained Athletes

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT03044444
Recruitment Status : Completed
First Posted : February 7, 2017
Last Update Posted : April 11, 2018
Sponsor:
Information provided by (Responsible Party):
BioActor

Brief Summary:
In this study, the effect of citrus extract on exercise performance will be investigated. The study consists of three groups: one group will receive a high dose citrus extract, one group will receive a low dose citrus extract and the last group will receive a placebo. After four and eight weeks the effects on performance are measured through a Triple Wingate cycling test, handgrip strength, vertical jump and 1600m run trial. It is expected that exercise performance will increase in the citrus extract groups, compared to the placebo group.

Condition or disease Intervention/treatment Phase
Exercise Performance Dietary Supplement: citrus extract Other: placebo Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 93 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose: Other
Official Title: Establishing the Effect of Long-term Citrus Extract Supplementation on Exercise-specific Performance in Moderately Trained Athletes
Actual Study Start Date : April 13, 2017
Actual Primary Completion Date : April 6, 2018
Actual Study Completion Date : April 6, 2018

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: high dose citrus extract
this group will receive a high dose (500mg/day) of the citrus extract for 8 weeks
Dietary Supplement: citrus extract
Participants will receive either a low or high dose citrus extract

Experimental: low dose citrus extract
this group will receive a low dose (400mg/day) of the citrus extract for 8 weeks
Dietary Supplement: citrus extract
Participants will receive either a low or high dose citrus extract

Placebo Comparator: placebo
this group will receive a placebo (500mg maltodextrin per day) for 8 weeks
Other: placebo
participants will receive 500mg of maltodextrin




Primary Outcome Measures :
  1. peak force output Wingate [ Time Frame: 8 weeks ]
    Peak force output in Watts during a high intensity repeated sprint cycling exercise


Secondary Outcome Measures :
  1. jumping height [ Time Frame: 8 weeks ]
    jumping height in cm measured during a vertical jump exercise

  2. peak force output Handgrip [ Time Frame: 8 weeks ]
    Peak force output in Watts during a handgrip strength test

  3. force output Jump [ Time Frame: 8 weeks ]
    force output in W measured during a vertical jump exercise

  4. anaerobic capacity [ Time Frame: 8 weeks ]
    total amount of power (W) generated in the first 30 seconds of the the triple Wingate cycle test

  5. running time [ Time Frame: 8 weeks ]
    running time in minutes and seconds measured over 1600m


Other Outcome Measures:
  1. lactate [ Time Frame: 8 weeks ]
    post-exercise blood lactate in mmol/L after triple Wingate cycle exercise test



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 35 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • healthy idividuals
  • Participants are amateur or (semi-) professional athletes in resistance or interval sports (engage in >4 hours of intense physical activity per week).

Exclusion Criteria:

  • Use of creatine supplements and/or anabolic steroids.
  • Allergy to test product/placebo
  • Allergy to citrus fruits
  • BMI lower than 18 or higher than 30
  • Recent muscle injury in less than one month before the start of the study.
  • Cardiovascular complications
  • Use of medication that may interfere with the study results
  • Administration of investigational drugs or participation in any scientific intervention study which may interfere with this study (to be decided by the principle investigator), in the 180 days prior to the study.
  • Abuse of products; alcohol (> 20 alcoholic units per week) and drugs.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03044444


Locations
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Netherlands
High Performance Center
Sittard, Limburg, Netherlands, 6135LG
Sponsors and Collaborators
BioActor
Investigators
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Principal Investigator: Freddy Troost, Dr. Maastricht University

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Responsible Party: BioActor
ClinicalTrials.gov Identifier: NCT03044444    
Other Study ID Numbers: HES_PER_002
First Posted: February 7, 2017    Key Record Dates
Last Update Posted: April 11, 2018
Last Verified: April 2018
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by BioActor:
performance
polyphenols
nutrition
sports