Evaluation of Cerebral Oxygenation and Hemodynamics in Patients With Cerebral Venous Thrombosis
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ClinicalTrials.gov Identifier: NCT03033966
Recruitment Status :
First Posted : January 27, 2017
Last Update Posted : January 27, 2017
Information provided by (Responsible Party):
Dhritiman Chakrabarti, National Institute of Mental Health and Neuro Sciences, India
Cerebral hypoperfusion and hypoxia are the major determinants of neurological outcomes following acute brain injury as proved in Traumatic Brain Injury/Sub Arachnoid Haemhorrhage literature. How the brain injury affects cerebral oxygenation in patients with CVT is not currently known. Some of the factors that can affect cerebral oxygenation in patients with CVT are Hemoglobin, PO2, PCO2, Cerebral Perfusion Pressure (or MAP) and change in Intracranial Pressure after Decompressive Craniectomy. This study is designed to study how these factors affect cerebral oxygenation and impact of Decompressive Craniectomy on the cerebral oxygenation.
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Layout table for eligibility information
Ages Eligible for Study:
16 Years to 65 Years (Child, Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patients with Cerebral venous thrombosis for Decompressive craniectomy
-Patients diagnosed with cerebral venous thrombosis, undergoing decompressive craniectomy.
Patients on inotropic support
Systolic blood pressure < 90 mmHg
Haemoglobin oxygen saturation <95%
Refusal of consent
Age <16 and > 65 years
Known history of diabetes or hypertension
Any contraindication for application of cerebral oximetry sensors