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Efficacy of Glycine Powder Air-Polishing Combined With Scaling and Root Planing in the Treatment of Periodontitis and Halitosis

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ClinicalTrials.gov Identifier: NCT03031756
Recruitment Status : Completed
First Posted : January 26, 2017
Last Update Posted : January 26, 2017
Sponsor:
Information provided by (Responsible Party):
Hasan Guney YILMAZ, Near East University, Turkey

Brief Summary:

The aim of this clinical study was to evaluate the clinical efficacy of using perio flow adjunctively with mechanical instrumentation on periodontal parameters and halitosis.

Sixty patients who presented with 4-6-mm probing pocket depth (PPD) were recruited for the study. Patients were randomly assigned to glycine powder air-polishing (GPAP) or control groups. For both groups PPDscores were recorded at the baseline and 1 month. Volatile sulphur compound (VSC) values were measured by a halimeter at the baseline, immediately after treatment, and at 7 days, 14 days and 1 month.


Condition or disease Intervention/treatment Phase
Halitosis Device: glycine powder air-polishing (Air-Flows)Perio Powder Device: ultrasonic (Piezon Master 700; EMS, Nyon, Switzerland) Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 60 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Supportive Care
Official Title: Efficacy of Glycine Powder Air-Polishing Combined With Scaling and Root Planing in the Treatment of Periodontitis and Halitosis: A Randomized Clinical Study
Study Start Date : January 2015
Actual Primary Completion Date : July 2015
Actual Study Completion Date : April 2016

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Bad Breath
Drug Information available for: Glycine

Arm Intervention/treatment
Experimental: test
SRP was performed using routine ultrasonic (Piezon Master 700; EMS, Nyon, Switzerland) and hand instrumentation, glycine powder air-polishing (GPAP) was performed for 10 seconds per surface after the instrumentation (Air-Flows Perio Powder, EMS, Nyon, Switzerland) was applied using a Perio-Flows hand-piece connected to an airflow unit (Air-Flow Masters, EMS).
Device: glycine powder air-polishing (Air-Flows)Perio Powder
Other Name: EMS, Nyon

Device: ultrasonic (Piezon Master 700; EMS, Nyon, Switzerland)
Other Name: EMS Piezon Master

Active Comparator: control
In the control group, SRP was performed using routine ultrasonic (Piezon Master 700; EMS, Nyon, Switzerland) and hand instrumentation.
Device: ultrasonic (Piezon Master 700; EMS, Nyon, Switzerland)
Other Name: EMS Piezon Master




Primary Outcome Measures :
  1. Periodontal Pocket Depth (PPD) [ Time Frame: 30 day. ]
    PD were evaluated:at the follow-up sessions by the investigator with by marking a point on a 10 mm periodontal probe.


Secondary Outcome Measures :
  1. halimeter values. [ Time Frame: 30 day. ]
    The changes of Volatile Sulphure Compaunds by were evaluated with Halimeter Device at the follow-up sessions by the investigator. The Halimeter reads out in parts-per-billion (ppb) of volatile sulfur compounds.



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Ages Eligible for Study:   28 Years to 68 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • In the present trial, patients who had at least three teeth with 4-6-mm periodontal pockets.

Exclusion Criteria:

  • acute infectious oral lesions,
  • furcation defects,
  • using antibiotics for any reason in the last 4 weeks,
  • periodontal treatment in the last 6 months and
  • pregnant or lactating patients.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03031756


Sponsors and Collaborators
Near East University, Turkey
Investigators
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Study Director: Hasan Guney YILMAZ, DDS,PhD Near East University, Faculty of Dentistry
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Responsible Party: Hasan Guney YILMAZ, Assoc Prof Dr, Near East University, Turkey
ClinicalTrials.gov Identifier: NCT03031756    
Other Study ID Numbers: 33-236-2015
First Posted: January 26, 2017    Key Record Dates
Last Update Posted: January 26, 2017
Last Verified: January 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No
Keywords provided by Hasan Guney YILMAZ, Near East University, Turkey:
Air polishing
Additional relevant MeSH terms:
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Periodontitis
Halitosis
Periodontal Diseases
Mouth Diseases
Stomatognathic Diseases
Signs and Symptoms, Digestive
Glycine
Glycine Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs