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Relationship of Cricoid With the Right and Left Bronchial Diameters in the Pediatric Population Using Three-dimensional Imaging.

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT03030781
Recruitment Status : Completed
First Posted : January 25, 2017
Last Update Posted : January 25, 2017
Information provided by (Responsible Party):
Tariq Wani, King Fahad Medical City

Brief Summary:
Specific and objective guidelines for choosing endobronchial tube size for main-stem intubation in pediatric patients are lacking. The objective criteria for choosing an ETT size for OLV are likely to increase the safety and success. The primary aims of this study were to define the relationship between cricoid and mainstem bronchi (right and left) in children of various ages and to determine the effects of age, height and weight.

Condition or disease
Larynx Oxygen Intubation

Detailed Description:

Understanding the relationship between cricoid and mainstem bronchi can provide to be a useful adjunct for lung isolation in children. The relationship between cricoid dimensions and the dimensions of main-stem bronchi (right and left) have been studied using 2 dimensional CT images and video-bronchoscopic images. The present study defines the volume-based relationship between the right main-stem bronchus (RMSB), left main-stem bronchus (LMSB) and the cricoid ring based on 3 dimensional CT derived images.

Methods: The three dimensional CT images of 35 children, younger than 8 years, undergoing radiological evaluation unrelated to airway symptomatology were examined. The children were evaluated during spontaneous ventilation without airway devices either during natural sleep or with sedation. The 3-dimensional images of the airway column were evaluated at the level of cricoid, right mainstem bronchus and left main-stem bronchus, volumes were calculated and comparisons made between these levels. Univariate and multivariate regression analysis was used to determine whether one or more of the variables (age, gender, height, weight and cricoid) had a predictable relationship to the RMSB and the LMSB diameter.

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Study Type : Observational
Actual Enrollment : 35 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Relationship of Cricoid With the Right and Left Bronchial Diameters in the Pediatric Population Using Three-dimensional Imaging.
Study Start Date : August 2016
Actual Primary Completion Date : November 2016
Actual Study Completion Date : November 2016

Primary Outcome Measures :
  1. comparison between cricoid and mainstem borncchi [ Time Frame: 1 month to 8 years ]

Information from the National Library of Medicine

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Ages Eligible for Study:   1 Month to 96 Months   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
The present study evaluated CT images of the chest of children less than 8 years of age. The database search of the electronic medical records identified 110 patients of which 40 patients qualified for the study.

Inclusion Criteria:

  • Children 1 month to 8 years of age

Exclusion Criteria:

  • Patients with tracheostomy Tracheoesophageal fistula Presence of mediastinal mass Diaphragmatic hernia Preterm infants
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Responsible Party: Tariq Wani, CONSULTANT ANESTHESIOLOGIST, King Fahad Medical City Identifier: NCT03030781    
Other Study ID Numbers: H-01-R-012, 17-010
First Posted: January 25, 2017    Key Record Dates
Last Update Posted: January 25, 2017
Last Verified: November 2016
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No