Long Term Extension Study to Assess the Safety and Efficacy of Filgotinib in Adults With Rheumatoid Arthritis (FINCH 4)
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT03025308 |
Recruitment Status :
Active, not recruiting
First Posted : January 19, 2017
Last Update Posted : October 21, 2022
|
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Rheumatoid Arthritis | Drug: Filgotinib Drug: Placebo to match filgotinib | Phase 3 |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 2731 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | None (Open Label) |
Masking Description: | This study was originally designed and initiated as a double-blind study but the study design will change to open-label following implementation of the protocol amendment # 4. |
Primary Purpose: | Treatment |
Official Title: | A Multicenter, Open-label, Long Term Extension Study to Assess the Safety and Efficacy of Filgotinib in Subjects With Rheumatoid Arthritis |
Actual Study Start Date : | February 28, 2017 |
Estimated Primary Completion Date : | April 2025 |
Estimated Study Completion Date : | May 2025 |

Arm | Intervention/treatment |
---|---|
Experimental: Blinded Phase: Filgotinib 200 mg
Filgotinib 200 mg plus placebo to match (PTM) filgotinib 100 mg for up to 6 years
|
Drug: Filgotinib
Tablet(s) administered orally once daily
Other Names:
Drug: Placebo to match filgotinib Tablet(s) administered orally once daily |
Experimental: Blinded Phase: Filgotinib 100 mg
Filgotinib 100 mg plus PTM filgotinib 200 mg for up to 6 years
|
Drug: Filgotinib
Tablet(s) administered orally once daily
Other Names:
Drug: Placebo to match filgotinib Tablet(s) administered orally once daily |
Experimental: Open Label Phase: Filgotinib 200 mg
Filgotinib 200 mg for up to 6 years
|
Drug: Filgotinib
Tablet(s) administered orally once daily
Other Names:
|
Experimental: Open Label Phase: Filgotinib 100 mg
Filgotinib 100 mg for up to 6 years
|
Drug: Filgotinib
Tablet(s) administered orally once daily
Other Names:
|
- Proportion of Participants Experiencing Adverse Events (AEs) [ Time Frame: Up to 6 years ]
- Proportion of Participants Experiencing Clinically Significant Laboratory Abnormalities [ Time Frame: Up to 6 years ]
- Proportion of Participants Achieving American College of Rheumatology- N (ACR-N) Response in Each Arm [ Time Frame: Up to 6 years ]

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 18 Years and older (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Key Inclusion Criteria:
-
Males or females who may benefit from filgotinib as judged by the investigator AND who completed a Gilead sponsored filgotinib parent study for RA as outlined below:
-
Have completed GS-US-417-0301, GS-US-417-0302 or GS-US-417-0303 on study drug
- OR
- Have completed GS-US-417-0302 on standard of care therapy due to RA non-responder status
-
- Females of childbearing potential must have a negative pregnancy test prior to first dose of study drug in the long term extension (LTE)
- Males and females of childbearing potential who engage in heterosexual intercourse must agree to protocol-approved methods of contraception
Key Exclusion Criteria:
- Diagnosis of an autoimmune or inflammatory joint disease other than RA, which would put the participant at risk by participating in the study or would interfere with study assessments/data interpretation, per judgment of the investigator
- Known hypersensitivity to the study drug or its excipients
- Any medical condition which would put the participant at risk by participating in the study or would interfere with study assessments/data interpretation, per judgment of the investigator
NOTE: Other protocol defined Inclusion/ Exclusion criteria may apply.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03025308


United States, Alabama | |
Rheumatology Associates of North Alabama, PC | |
Huntsville, Alabama, United States, 35801 | |
United States, Arizona | |
Arthrocare, Arthritis Care & Research PC | |
Gilbert, Arizona, United States, 85234 | |
Arizona Arthritis & Rheumatology Associates, P.C. | |
Phoenix, Arizona, United States, 85037 | |
Arizona Arthritis & Rheumatology Associates, P.C. | |
Tucson, Arizona, United States, 85704 | |
United States, California | |
Medvin Clinical Research | |
Covina, California, United States, 91722 | |
C.V. Mehta M.D. Medical Corporation | |
Hemet, California, United States, 92543 | |
University of California San Diego (UCSD) - Perlman Ambulatory Clinic | |
La Jolla, California, United States, 92037 | |
Keck Medicine of USC- Division of Rheumatology | |
Los Angeles, California, United States, 90033 | |
Desert Medical Advances | |
Palm Desert, California, United States, 92260 | |
Stanford University Hospitals and Clinics (Immunology & Rheumatology) | |
Palo Alto, California, United States, 94305 | |
C.V. Mehta Medical Corporation | |
Riverside, California, United States, 92518 | |
Inland Rheumatology Clinical Trials, Inc. | |
Upland, California, United States, 91786 | |
Desert Valley Medical Group | |
Victorville, California, United States, 92395 | |
Medvin Clinical Research | |
Whittier, California, United States, 90602 | |
United States, Florida | |
AARDS Research, Inc. | |
Aventura, Florida, United States, 33180 | |
Clinical Research of West Florida, Inc. | |
Clearwater, Florida, United States, 33765 | |
Omega Research Consultants, LLC | |
DeBary, Florida, United States, 32713 | |
University of Florida College of Medicine, Jacksonville - Rheumatology Research | |
Jacksonville, Florida, United States, 32207 | |
San Marcus Research Clinic, Inc. | |
Miami Lakes, Florida, United States, 33014 | |
Suncoast Research Group, LLC | |
Miami, Florida, United States, 33135 | |
Suncoast Clinical Research, Inc. | |
New Port Richey, Florida, United States, 34652 | |
Omega Research Consultants LLC | |
Orlando, Florida, United States, 32804 | |
IRIS Research and Development, LLC | |
Plantation, Florida, United States, 33324 | |
United States, Georgia | |
Jefrey D. Lieberman, MD, P.C. | |
Decatur, Georgia, United States, 30033 | |
United States, Illinois | |
Springfield Clinic | |
Springfield, Illinois, United States, 62702 | |
United States, Kansas | |
University of Kansas Medical Center | |
Kansas City, Kansas, United States, 66160 | |
Heartland Research Associates, LLC | |
Wichita, Kansas, United States, 67207 | |
United States, Kentucky | |
Center For Arthritis and Osteoporosis | |
Elizabethtown, Kentucky, United States, 42701 | |
Bluegrass Community Research, Inc. | |
Lexington, Kentucky, United States, 40504 | |
United States, Maryland | |
Klein & Associates, M.D., P.A. | |
Cumberland, Maryland, United States, 21502 | |
Arthritis Treatment Center | |
Frederick, Maryland, United States, 21702 | |
Klein & Associates, M.D., P.A. | |
Hagerstown, Maryland, United States, 21740 | |
The Center For Rheumatology And Bone Research | |
Wheaton, Maryland, United States, 20902 | |
United States, Massachusetts | |
Clinical Pharmacology Study Group | |
Worcester, Massachusetts, United States, 01605 | |
Umass Memorial Medical Center- Memorial Campus | |
Worcester, Massachusetts, United States, 01605 | |
United States, Michigan | |
Henry Ford Health System | |
Detroit, Michigan, United States, 48202 | |
Shores Rheumatology, PC | |
Saint Clair Shores, Michigan, United States, 48081 | |
United States, Minnesota | |
St. Paul Rheumatology, PA | |
Eagan, Minnesota, United States, 55121 | |
United States, Mississippi | |
Arthritis Associates, PLLC | |
Hattiesburg, Mississippi, United States, 39402 | |
North Mississippi Medical Clinics, Inc. | |
Tupelo, Mississippi, United States, 38801 | |
United States, Missouri | |
Clayton Medical Research, P.C. | |
Saint Louis, Missouri, United States, 63117 | |
Arthritis Consultants, Inc. | |
Saint Louis, Missouri, United States, 63141 | |
United States, Nebraska | |
Physician Research Collaboration, LLC | |
Lincoln, Nebraska, United States, 68516 | |
United States, New Hampshire | |
Dartmouth-Hitchcock Medical Center | |
Lebanon, New Hampshire, United States, 03756 | |
United States, New Jersey | |
Arthritis & Osteoporosis Associates | |
Freehold, New Jersey, United States, 07728 | |
Ocean Rheumatology, PA | |
Toms River, New Jersey, United States, 08755 | |
United States, New Mexico | |
Albuquerque Clinical Trials, Inc. | |
Albuquerque, New Mexico, United States, 87102 | |
United States, New York | |
NYU Langone Ambulatory Care Brooklyn Heights | |
Brooklyn, New York, United States, 11201 | |
Weill Cornell Physicians At Brooklyn Heights | |
Brooklyn, New York, United States, 11201 | |
United States, North Carolina | |
Joint And Muscle Research Institute | |
Charlotte, North Carolina, United States, 28204 | |
Physicians East, PA | |
Greenville, North Carolina, United States, 27834 | |
PMG Research of Salisbury | |
Salisbury, North Carolina, United States, 28144 | |
United States, Ohio | |
Paramount Medical Research & Consulting, LLC | |
Middleburg Heights, Ohio, United States, 44130 | |
United States, Oklahoma | |
Health Research of Oklahoma | |
Oklahoma City, Oklahoma, United States, 73103 | |
The Oklahoma Center For Arthritis Therapy & Research, Inc. | |
Tulsa, Oklahoma, United States, 74104 | |
United States, Pennsylvania | |
East Penn Rheumatology Associates | |
Bethlehem, Pennsylvania, United States, 18015 | |
Altoona Center for Clinical Research | |
Duncansville, Pennsylvania, United States, 16635 | |
Arthritis Group, PC | |
Philadelphia, Pennsylvania, United States, 19152 | |
Clinical Research Center of Reading LLC | |
Wyomissing, Pennsylvania, United States, 19610 | |
PA Regional Center For Arthritis And Osteoporosis Research | |
Wyomissing, Pennsylvania, United States, 19610 | |
United States, South Carolina | |
Articularis Healthcare Inc., dba Columbia Arthritis Center, PA | |
Columbia, South Carolina, United States, 29204 | |
Carolina Rheumatology & Neurology Assoc., PC | |
Myrtle Beach, South Carolina, United States, 29572 | |
Articularis Healthcare Group d/b/a ACME Research | |
Orangeburg, South Carolina, United States, 29118 | |
Articularis Healthcare Group d/b/a Low Country Rheumatology | |
Summerville, South Carolina, United States, 29486 | |
United States, Tennessee | |
Ramesh C. Gupta, M.D. | |
Memphis, Tennessee, United States, 38119 | |
United States, Texas | |
Diagnostic Group | |
Beaumont, Texas, United States, 77701 | |
Trinity Universal Research Associates, Inc | |
Carrollton, Texas, United States, 75007 | |
Adriana Pop-Moody MD Clinic PA | |
Corpus Christi, Texas, United States, 78404 | |
Arthritis Centers Of Texas | |
Dallas, Texas, United States, 75246 | |
Southwest Rheumatology Research, LLC | |
Mesquite, Texas, United States, 75150 | |
Trinity Universal Research Associates, Inc | |
Plano, Texas, United States, 75024 | |
Arthritis & Osteoporosis Center of South Texas | |
San Antonio, Texas, United States, 78232 | |
Argentina | |
Ceim Investigaciones Medicas Srl | |
Ciudad Autonoma, Buenos Aires, Argentina, 1425 | |
CIMEL | |
Buenos Aires, Argentina, B1824KAJ | |
Onganizacion Medica de Investigacion S.A (OMI) | |
Ciudad Autonoma Buenos Aires, Argentina, C1015ABO | |
Mautalen Salud e Investigación | |
Ciudad Autonoma Buenos Aires, Argentina, C1128AAF | |
Consultorios Reumatológicos Pampa | |
Ciudad Autonoma de Buenos Aire, Argentina, C1428DZF | |
Investigaciones Reumatologicas Y Osteologicas (IRO) SRL | |
Ciudad Autonoma, Argentina, C1114AHH | |
Instituto De Reumatologia | |
Mendoza, Argentina, 5500 | |
Instituto Médico Cer | |
Quilmes, Argentina, B1878DVB | |
Instituto Iari | |
San Isidro, Argentina | |
Cer San Juan, Centro Polivalente de Asistencia e Investigacion Clinica | |
San Juan, Argentina, CP5400 | |
Centro Medico Privado de Reumatología | |
San Miguel de Tucuman, Argentina, T4000AXL | |
Australia, Queensland | |
Rheumatology Research Unit | |
Maroochydore, Queensland, Australia, 4558 | |
Australia, Western Australia | |
RK Will Pty Ltd | |
Victoria Park, Western Australia, Australia, 6100 | |
Australia | |
Southern Clinical Research Pty Ltd | |
Hobart, Australia, 7000 | |
Belgium | |
Cliniques Universitaires Saint-Luc | |
Brussels, Belgium, 1200 | |
Reumaclinic Genk | |
Genk, Belgium, 3600 | |
Universitaire Ziekenhuizen (UZ) Leuven - Gasthuisberg | |
Leuven, Belgium, 3000 | |
Zna Jan Palfijn | |
Merksem, Belgium, 2170 | |
Bulgaria | |
"Medical Center Help" EOOD | |
Dobrich, Bulgaria, 9300 | |
"Medical Center- Hipokrat 2000" OOD | |
Haskovo, Bulgaria, 6300 | |
"UMHAT - Kaspela" EOOD | |
Plovdiv, Bulgaria, 4001 | |
"MHAT Lyulin" EAD, Department of Rheumatology | |
Sofia, Bulgaria, 1336 | |
Medical Center "N. I. Pirogov" EOOD | |
Sofia, Bulgaria, 1612 | |
"DCC Equita" EOOD | |
Varna, Bulgaria, 9000 | |
MHAT "Sveta Petka" AD, Department of Internal Diseases | |
Vidin, Bulgaria, 3700 | |
Canada | |
The Waterside Clinic | |
Barrie, Canada, L4M6L2 | |
Centre De Recherche Musculo Squelettique | |
Trois Rivieres, Canada, G8Z1Y2 | |
Chile | |
Quantum Research Santiago | |
Santiago, Chile, 7500588 | |
Someal SA | |
Santiago, Chile, 7510186 | |
Centro Medico De Reumatologia | |
Temuco, Chile, 4790928 | |
Czechia | |
MUDr. Michaela Blahova, revmatologicka ambulance s.r.o. | |
Brno, Czechia, 60200 | |
L.K.N. Arthrocentrum, s.r.o. | |
Hlucin, Czechia, 748 01 | |
MUDr. Rosypalová, S.R.O. | |
Ostrava-Poruba, Czechia, 70800 | |
Revmatologicky ustav | |
Prague 2, Czechia, 12850 | |
Arthrocentrum spol.s.r.o. | |
Prague Praha 10, Czechia, 10100 | |
Revmatologicka Ambulance | |
Praha 4, Czechia, 140 00 | |
Revmatologicka ambulance, Nuselska Poliklinika | |
Praha 4, Czechia, 14000 | |
Medical Plus, S.R.O. | |
Uherske Hradiste, Czechia, 68601 | |
France | |
Hôpital Lapeyronie, Service d'Immuno-Rhumatologic | |
Montpellier Cedex 5, France, 34295 | |
Germany | |
Rheumapraxis Dr. med. Reiner Kurthen | |
Aachen, Germany, 52064 | |
Schlosspark-Klinik | |
Berlin, Germany, 14059 | |
Centrum f. inn. Diagn. und Therap. Rheumatologie/Immunologie | |
Frankfurt am Main, Germany, 60590 | |
HRF II, Hamburger Rheuma Forsch. Zentrum II, MVZ f. Rheumatologie und Autoimmuned. Hamb. GmbH/ Dr. A. Everding GbR | |
Hamburg, Germany, 20095 | |
Rheumazentrum Ratungen-Studienambulanz GbR | |
Ratingen, Germany, 40878 | |
Hong Kong | |
Department of Medicine & Theraputics, The Chinese University of Hong Kong | |
Hong Kong, Hong Kong | |
Department of Medicine, Queen Mary Hospital | |
Hong Kong, Hong Kong | |
Tuen Mun Hospital | |
Hong Kong, Hong Kong | |
Hungary | |
Betegapolo-Irgalmasrend Budai Irgalmasrendi Korhaz | |
Budapest, Hungary, 1023 | |
Revita Reumatológiai Kft. | |
Budapest, Hungary, 1027 | |
Markhot Ferenc Oktatokorhaz es Rendelointezet; Reumatologiai Osztaly | |
Eger, Hungary, 3300 | |
Bekes Megyei Kozponti Korhaz, Pandy Kalman Tagkorhaz, Reumatologiai Osztaly | |
Gyula, Hungary, 5700 | |
Bacs Kiskun Megyei Korhaz Szedgedi Tudomanyegyetem Altalanos Orvostudomanyi Kar Oktatokorhaz Kalocsai Szent Kereszt Korh | |
Kalocsa, Hungary, 6300 | |
Pest Megyei Flor Ferenc Korhaz, Reumatologiai-es Fizioterapias Osztaly | |
Kistarcsa, Hungary, 2143 | |
Csongrad Megyei Dr. Bugyi Istvan Korhaz; Mozgasszervi Rehabilitacios Osztaly | |
Szentes, Hungary, 6600 | |
C-Med Rehabilitacios es Diagnosztikai Kozpont. Reumatologia | |
Székesfehérvár, Hungary, 8000 | |
India | |
Panchshil Hospital, Dep | |
Ahmedabad, India, 380005 | |
B.J. Medical College and Civil Hospital | |
Ahmedabad, India, 380016 | |
Chanre Rheumatology and Immunology Centre and Research | |
Bangalore, India, 560010 | |
Chennai Meenakshi Multispeciality Hospital Ltd | |
Chennai, India, 600004 | |
All India Institute of Medical Sciences | |
Delhi, India, 110029 | |
Medanta - The Medicity | |
Gurgaon, India, 122001 | |
Gleneagles Global Hospitals | |
Hyderabad, India, 500004 | |
Nizams Institute of Medical Sciences | |
Hyderabad, India, 50082 | |
Shri Nidaan Hospital and Hope Fertility Centre | |
Jaipur, India, 302001 | |
SR Kalla Memorial Gastro and General Hospital | |
Jaipur, India, 302001 | |
Santokba Durlabhji Memorial Hospital Cum Medical Research Institute | |
Jaipur, India, 302015 | |
Apollo Gleneagles Hospitals, Kolkata | |
Kolkata, India, 700 054 | |
Medical College & Hospital, Kolkata | |
Kolkata, India, 700073 | |
Department of Rheumatology, KG Medical University | |
Lucknow, India, 226018 | |
Kasturba Medical College Hospital | |
Mangalore, India, 575001 | |
Vinaya Hospital and Research Centre | |
Mangalore, India, 575003 | |
JSS Medical College and Hospital | |
Mysuru, India, 570004 | |
Suretech Hospital and Research Centre Pvt Ltd | |
Nagpur, India, 440012 | |
Maharaja Agrasen Hospital | |
New Delhi, India, 110026 | |
Sir Ganga Ram Hospital | |
New Delhi, India, 110060 | |
Centre for Rheumatic Disease, Hermes Doctor House | |
Pune, India, 411001 | |
Deenanath Mangeshkar Hospital and Research Centre | |
Pune, India, 411004 | |
Krishna Institute of Medical Sciences | |
Secunderabad, India | |
Rajiv Gandhi Institute of Medical Sciences and Government General Hospital | |
Srikakulam, India, 532001 | |
Nirmal Hospital Private Limited | |
Surat, India, 395002 | |
Medical College Baroda and Sir Sayajirao General Hospital | |
Vadodara, India, 390001 | |
King George Hospital | |
Visakhapatnam, India, 530002 | |
Ireland | |
St Vincent's University Hospital | |
Dublin, Ireland, Dublin 4 | |
Israel | |
Bnai Zion Medical Center | |
Haifa, Israel, 3339419 | |
The Lady Davis Carmel Medical Center | |
Haifa, Israel, 3436212 | |
Rabin Medical Center | |
Petah Tikva, Israel, 4941492 | |
The Chaim Sheba Medical Center | |
Ramat Gan, Israel, 5265601 | |
Tel Aviv Medical Center | |
Tel Aviv, Israel, 6423906 | |
Italy | |
Departimento Cardio-toraco-vascolare Gestione delle Malattie Reumatiche e del Connettivo e Malattie Metaboliche dell'osso | |
Bologna, Italy, 40138 | |
Reumatologia | |
Milano, Italy, 20157 | |
Japan | |
Chibaken Saiseikai Narashino Hospital | |
Narashino, Chiba, Japan, 275-8580 | |
Medical Corporation Kojyokai Hirose Clinic | |
Tokorozawa, Saitama, Japan, 359-1111 | |
Honjo Rheumatism Clinic | |
Takaoka, Toyama, Japan, 933-0874 | |
Chiba University Hospital | |
Chiba-shi, Japan, 2608677 | |
Kyushu Medical Center | |
Fukuoka, Japan, 810-8563 | |
National Hospital Organization Kyushu Medical Center | |
Fukuoka, Japan, 810-8563 | |
Seirei Hamamatsu General Hospital | |
Hamamatsu, Japan, 430-8558 | |
Hiroshima Rheumatology Clinic | |
Hiroshima-shi, Japan, 730-0017 | |
Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital | |
Hiroshima, Japan, 730-8619 | |
Hiroshima University Hospital | |
Hiroshima, Japan, 734-8551 | |
Iizuka Hospital | |
Iizuka-shi, Japan, 820-8505 | |
Saitama Medical University Hospital | |
Iruma-gun, Japan, 350-0495 | |
Shimane University Hospital | |
Izumo, Japan, 693-8501 | |
Kagoshima red cross hospital | |
Kagoshima-shi, Japan, 891-0133 | |
Matsubara Mayflower Hospital | |
Kato, Japan, 673-1462 | |
Saitama Medical Center | |
Kawagoe, Japan, 350-8550 | |
Hospital of the University of Occupational and Environmental Health, Japan | |
Kitakyushu-shi, Japan, 807-8556 | |
Kobe University Hospital | |
Kobe, Japan, 650-0017 | |
Kumamoto Orthopaedic Hospital | |
Kumamoto-shi, Japan, 862-0975 | |
Kurume University Medical Center | |
Kurume-shi, Japan, 839-0863 | |
Kyoto University Hospital | |
Kyoto-shi, Japan, 606-8507 | |
University Hospital, Kyoto Prefectural University of Medicine | |
Kyoto, Japan, 602-8566 | |
Yu Family Clinic | |
Miyagi-gun, Japan, 981-0112 | |
Zenjinkai Shiminnnomori Hospital | |
Miyazaki, Japan, 880-0122 | |
Yoshida orthopaedic and rheumatology Clinic | |
Morioka-shi, Japan, 020-0015 | |
Nagaoka Red Cross Hospital | |
Nagaoka, Japan, 940-2085 | |
Nagasaki Medical Hospital of Rheumatology | |
Nagasaki-shi, Japan, 850-0832 | |
Nagoya University Hospital | |
Nagoya, Japan, 466-8560 | |
The Hospital of Hyogo College of Medine | |
Nishinomiya, Japan, 663-8501 | |
Okayama Saiseikai General Hospital Outpatient Center | |
Okayama-city, Japan, 700-0013 | |
Okayama University Hospital | |
Okayama, Japan, 700-8558 | |
Ome Municipal General Hospital | |
Ome, Japan, 198-0042 | |
National Hospital Organization Sagamihara National Hospital | |
Sagamihara, Japan, 252-0392 | |
Sanuki Municipal Hospital | |
Sanuki-shi, Japan, 769-2393 | |
Sagawa Akira Rheumatology Clinic | |
Sapporo, Japan, 060-0001 | |
Sapporo City General Hospital | |
Sapporo, Japan, 060-8604 | |
Hokkaido University Hospital | |
Sapporo, Japan, 060-8648 | |
Hokkaido Medical Center for Rheumatic Diseases | |
Sapporo, Japan, 063-0811 | |
Sasebo Chuo Hospital | |
Sasebo-shi, Japan, 857-1195 | |
Azuma Rheumatology Clinic | |
Sayama-shi, Japan, 350-1305 | |
Niigata Rheumatic Center | |
Shibata-City, Japan, 957-0054 | |
Shizuoka Welfare Hospital | |
Shizuoka, Japan, 420-8623 | |
Osaka University Hospital | |
Suita-shi, Japan, 565-0871 | |
Inoue Hospital | |
Takasaki-shi, Japan, 370-0053 | |
St. Luke's International Hospital | |
Tokyo, Japan, 104-8560 | |
Medical Corporation Uchida Clinic | |
Tokyo, Japan, 130-0013 | |
Showa University East Hospital | |
Tokyo, Japan, 142-0054 | |
Toho University Omori Medical Center | |
Tokyo, Japan, 143-8541 | |
Toho University Ohashi Medical Center | |
Tokyo, Japan, 153-8515 | |
Setagaya Rheumatic Clinic | |
Tokyo, Japan, 156-0052 | |
Keio University Hospital | |
Tokyo, Japan, 160-8582 | |
Teikyo University Hospital | |
Tokyo, Japan, 173-8606 | |
Yuuai Medical Center | |
Tomigusuku-shi, Japan, 901-0224 | |
University of Tsukuba Hospital | |
Tsukuba-shi, Japan, 305-8576 | |
Wakayama Medical University Hospital | |
Wakayama, Japan, 641-8509 | |
Yokohama Minami Kyousai Hospital | |
Yokohama-shi, Japan, 236-0037 | |
Korea, Republic of | |
Pusan National University Hospital | |
Busan-si, Korea, Republic of, 49241 | |
Kyungpook National University Hospital | |
Daegu, Korea, Republic of, 41944 | |
Daegu Catholic University Medical Center | |
Daegu, Korea, Republic of, 42472 | |
Chungnam National University Hospital | |
Daejeon, Korea, Republic of, 35015 | |
Eulji University Hospital | |
Daejeon, Korea, Republic of, 35233 | |
Chonnam National University Hospital | |
Gwangju, Korea, Republic of, 61469 | |
Inha University Hospital | |
Incheon, Korea, Republic of, 22332 | |
Chonbuk National University Medical School | |
Jeonju, Korea, Republic of, 54907 | |
Seoul National University Hospital | |
Seoul, Korea, Republic of, 03080 | |
Hanyang University Seoul Hospital | |
Seoul, Korea, Republic of, 04763 | |
Konkuk University Medical Center | |
Seoul, Korea, Republic of, 05030 | |
Asan Medical Center | |
Seoul, Korea, Republic of, 05505 | |
Chung-Ang University Hospital Institutional Review Board | |
Seoul, Korea, Republic of, 06973 | |
SMG-SNU Boramae Medical Center | |
Seoul, Korea, Republic of, 07061 | |
Malaysia | |
Hospital Selayang | |
Batu Caves, Selangor, Malaysia, 68100 | |
University Malaya Medical Centre | |
Kuala Lumpur, Malaysia, 59100 | |
Mexico | |
Centro De Investigación Clínica De Morelia, Sc | |
Morelia, Michoacan, Mexico, 58070 | |
Kohler & Milstein Research S.A. de C.V. | |
Mérida, Yucatan, Mexico, 97070 | |
Investigacion y Biomedicina de Chihuahua, S.C. | |
Chihuahua, Mexico, 31000 | |
Clinstile, S.A. De C.V. | |
Ciudad de Mexico, Mexico, 06700 | |
Clinosar Mexico. S.A. de C. V. | |
Ciudad de México, Mexico, 06760 | |
Centro Peninsular De Investigacion Clinica S.C.P. | |
Merida, Mexico, 97000 | |
Biologicos Especializados | |
Mexico, Mexico, 06700 | |
Hospital Universitario Dr. Jose Eleuterio Gonzalez | |
Monterrey, Mexico, 64460 | |
New Zealand | |
Middlemore Clinical Trial | |
Papatoetoe, Auckland, New Zealand, 2025 | |
Optimal Clinical Trials, Level 2 | |
Auckland, New Zealand, 1010 | |
Waikato Hospital | |
Hamilton, New Zealand, 3240 | |
Clinical Trial Unit, CCHDB, Wellington Hospital | |
Newtown, New Zealand, 6021 | |
Clinical Trials Unit, Timaru Hospital | |
Timaru, New Zealand, 7910 | |
Poland | |
Gabinet Internistyczno-Reumatologiczny Piotr Adrian Klimiuk | |
Bialystok, Poland, 15-099 | |
Clinicmed | |
Bialystok, Poland, 15-879 | |
Szpital Uniwersytecki Nr 2, Klinka Reumatologii I Ukladowych Chorob Tkanki Lacznej | |
Bydgoszcz, Poland, 85168 | |
Niepubliczny Zaklad Opieki Zdrowotnej BIF-MED S.C. | |
Bytom, Poland, 41-902 | |
Nszoz Unica Cr | |
Dabrówka, Poland, 62096 | |
Centrum Kliniczno-Badawcze J. Brzezicki | |
Elblag, Poland, 82300 | |
Centrum Medyczne Pratia Gdynia | |
Gdynia, Poland, 81-338 | |
NZOZ Centrum Medyczna Sw. Lukasza w Kartuzach | |
Kartuzy, Poland, 83300 | |
SILMEDIC Spolka z ograniczona odpowiedzialnoscia w Swindniku, Oddzial w Katowicach | |
Katowice, Poland, 40-282 | |
Nzoz Centrum Medyczne Promimed | |
Krakow, Poland, 31-637 | |
Twoja Przychodnia -Centrum Medyzcne Nowa Sol | |
Nowa Sol, Poland, 67-100 | |
Synexus Polska Sp. z.o.o. Oddzial w Porznaniu | |
Poznan, Poland, 60-702 | |
Centrum Badan Klinicznych S.C. Wieslawa Porawska, Lukasz Porawski | |
Poznan, Poland, 60-733 | |
Ai Centrum Medyczne | |
Poznan, Poland, 61-113 | |
Samodzielny Publiczny Zespol Opieki Zdrowotnej w Tomaszowie Lubelskim Lubelskim; Oddzial Reumatologiczy | |
Tomaszów Lubelski, Poland, 22-600 | |
Nasz Lekarz Przychodnie Medyczne | |
Torun, Poland, 87100 | |
Reumatika -Centrum Reumatologii NZOZ | |
Warszawa, Poland, 02-691 | |
Centrum Medyczne AMED Warszawa Targówek | |
Warszawa, Poland, 03291 | |
Centrum Medyczne Oporow | |
Wroclaw, Poland, 52416 | |
Romania | |
Spitalul Judetean de Urgenta Bacau, Sectia Reumatologie | |
Bacau, Romania, 600114 | |
S.C. Ianuli Med Consult S.R.L. | |
Bucuresti, Romania, 010976 | |
Spitalul Clinic ,, Sf. Maria", Sectia Reumatologie | |
Bucuresti, Romania, 011172 | |
Spitalul Clinic,, Sf. Maria"", Departamentul de Medicina Interna si Reumatologie | |
Bucuresti, Romania, 011172 | |
Spitalul Clinic Judetean de Urgenta Tirgu Mures | |
Targu-Mures, Romania, 540136 | |
Russian Federation | |
Territorial State Budgetary Healthcare Institution "Territorial Clinical Hospital" | |
Barnaul, Russian Federation, 656024 | |
State Budgetary Healthcare Institution, Chelyabinsk Regional Clinical Hospital | |
Chelyabinsk, Russian Federation, 454076 | |
FSBEI of HE "Kazan State Medical University" of Ministry of Healthcare of the Russia Federation, Department of hospital therapy | |
Kazan, Russian Federation, 420103 | |
Medical Center Maximum Zdorovia LLC | |
Kemerovo, Russian Federation, 650066 | |
Kemerovo State Medical University on the base of Regional Clinical Hospital for War Veterans | |
Kemerovo, Russian Federation, 650099 | |
Municipal Clinical Hospital No. 15 named after O.M. Filatov | |
Moscow, Russian Federation, 111539 | |
City Clinical Hospital #4 of Department of Healthcare of Moscow City | |
Moscow, Russian Federation, 115093 | |
M. Vladimirsky Moscow Regional Research Clinical Institute | |
Moscow, Russian Federation, 129110 | |
Municipal Clinical Hospital No. 40 Department of healthcare of Moscow City | |
Moscow, Russian Federation, 129301 | |
Nizhny Novgorod City Clinical Hospital #5 | |
Nizhny Novgorod, Russian Federation, 603005 | |
Saint-Petersburg State Budgetary Healthcare Institution "Clinical rheumatology hospital # 25" | |
Saint Petersburg, Russian Federation, 190068 | |
State Healthcare Institution, Regional Clinical Hospital | |
Saratov, Russian Federation, 410053 | |
LLC Polyclinic of Private Security Personnel | |
St.Petersburg, Russian Federation, 192007 | |
LLC BioMed | |
Vladimir, Russian Federation, 600005 | |
State Autonomous Healthcare Institution of Yaroslavl region "Clinical Hospital for Emergency Medical Care n. a. N. V. Solovyev" | |
Yaroslavl, Russian Federation, 150003 | |
Serbia | |
Institute Of Rheumatology | |
Belgrade, Serbia, 11000 | |
Military Medical Academy, Clinic of Rheumatology | |
Belgrade, Serbia, 11000 | |
Clinical Hospital Center Bezanijska Kosa | |
Belgrade, Serbia, 11080 | |
Institute For Treatment And Rehabilitation Niska Banja | |
Niska Banja, Serbia, 18205 | |
Slovakia | |
Neštátna Reumatologická Ambulancia | |
Bratislava, Slovakia, 841 04 | |
Reumex S.R.O. | |
Rimavská Sobota, Slovakia, 97901 | |
LERAM s.r.o. | |
Topolcany, Slovakia, 95501 | |
South Africa | |
Arthritis Clinical Trial Centre | |
Cape Town, South Africa, 7505 | |
Netcare St. Augustine's Hospital | |
Durban, South Africa, 4001 | |
Umhlanga Netcare Medical Centre | |
Durban, South Africa, 4319 | |
Charlotte Maxeke Johannesburg Academic Hospital | |
Johannesburg, South Africa, 2193 | |
Winelands Medical Research Centre | |
Stellenbosch, South Africa | |
Spain | |
Hospital Universitario Cruces | |
Barakaldo, Spain, 48903 | |
Complejo Hospitalario Universitario de Santiago | |
La Coruña, Spain, 15706 | |
Hospital General Universitario Gregorio Maranon | |
Madrid, Spain, 28007 | |
Hospital Universitario Ramon y Cajal | |
Madrid, Spain, 28034 | |
Hospital Regional Universitario de Malaga | |
Málaga, Spain, 29009 | |
Corporacio Santiaria Parc Tauli | |
Sabadell, Spain, 08208 | |
Clínica Gaias | |
Santiago de Compostela, Spain, 15702 | |
Hospital HM Nuestra Senora de la Esperanza | |
Santiago de Compostela, Spain, 15705 | |
Hospital Clinico Universitario de Valencia | |
Valencia, Spain, 46010 | |
Taiwan | |
Changhua Christian Hospital | |
Changhua City, Taiwan, 500 | |
Kaohsiung Veterans General Hospital | |
Kaohsiung, Taiwan, 813 | |
Chang Gung Memorial Hospital, Keelung | |
Keelung, Taiwan, 204 | |
China Medical University Hospital | |
Taichung City, Taiwan, 404 | |
Chung Shan Medical University Hospital | |
Taichung, Taiwan, 40201 | |
Chi Mei Hospital, Chi Mei Medical Center | |
Tainan City, Taiwan, 710 | |
National Taiwan University Hospital | |
Taipei, Taiwan, 100 | |
Taipei Medical University Hospital | |
Taipei, Taiwan, 110 | |
Tri-Service General Hospital | |
Taipei, Taiwan, 11490 | |
Chang Gung Medical Foundation, Chang Gung Memorial Hospital, Linkou Branch | |
Taoyuan, Taiwan, 333 | |
Thailand | |
Phramongkutklao Hospital, Division of Rheumatology, Department of Medicine | |
Bangkok, Thailand, 10400 | |
Rajavithi Hospital, Rheumatology and Allergy Unit | |
Bangkok, Thailand, 10400 | |
Faculty of Medicine Siriraj Hospital, Mahidol University, Division of Rheumatology, Department of Medicine | |
Bangkok, Thailand, 10700 | |
Maharaj Nakorn Chiang Mai Hospital, Faculty of Medicine, Chiang Mai University | |
Chiangmai, Thailand, 50200 | |
Faculty of Medicine, Prince of Songkla University, Songklanagarind Hospital | |
Songkla, Thailand, 90110 | |
Ukraine | |
Municipal Institution Dnipropetrovsk 6th City Clinical Hospital of Dnipropetrovsk Regional Council | |
Dnipro, Ukraine, 49074 | |
Municipal Nonprofit Enterprise of the Kharkiv Regional Council, Regional Hospital for War Veterans, Department of Therapy #1 | |
Kharkiv, Ukraine, 61019 | |
State Institution "National Institute of Therapy named after L.T. Maloyi" of National Academy of Medical Sciences of Ukraine" | |
Kharkiv, Ukraine, 61039 | |
Municipal Institution of Heath Care "Regional Clinical Hospital-Center Of Emergency Medicine & Disaster Medicine" | |
Kharkiv, Ukraine, 61058 | |
Municipal Nonprofit Enterprise "City Clinical Hospital #13" of the Kharkiv City Council, Department of Therapy | |
Kharkiv, Ukraine, 61124 | |
Minicipal Institution "Kherson City Clinical Hospital n. a. Afanasiy and Olga Tropinykh", Department of Therapy #1 | |
Kherson, Ukraine, 73000 | |
Kyiv Oleksandrivska City Clinical Hospital, Department of Rheumatology # 2 | |
Kyiv, Ukraine, 01601 | |
Kyiv City Clinical Hospital #6, Department of Therapy | |
Kyiv, Ukraine, 03126 | |
State Institution National Scientific Center M.D. Strazhesko Institute of Cardiology of NAMS of Ukraine | |
Kyiv, Ukraine, 03680 | |
Municipal Institution of Kyiv Regional Council "Kyiv Regional Clinical Hospital", Highly Specialized Therapeutic Department | |
Kyiv, Ukraine, 04107 | |
Lutsk City Clinical Hospital | |
Lutsk, Ukraine, 43024 | |
Municipal Institution of Lviv Regional Council "Lviv Regional Clinical Hospital" Department of Rheumatology | |
Lviv, Ukraine, 79010 | |
Municipal Nonprofit Enterprise "4-th City Clinical Hospital in Lviv", Department of Rheumatology | |
Lviv, Ukraine, 79011 | |
Municipal Institution Odesa Regional Clinical Hospital, Polyclinic Department | |
Odesa, Ukraine, 65025 | |
City Clinical Hospital #1, Department of Rheumatology | |
Vinnytsia, Ukraine, 21029 | |
Vinnytsya Regional Clinical Hospital named after M. I. Pyrogova, Department of Rheumatology | |
Vinnytsya, Ukraine, 21018 | |
Medical Centre Modern Clinic, LLC | |
Zaporizhzhya, Ukraine, 69005 | |
Municipal Institution "City Hospital #1", Department of Therapy | |
Zaporizhzhya, Ukraine, 69104 | |
Municipal Institution City Hospital #7, Department of Therapy | |
Zaporizhzhya, Ukraine, 69118 | |
United Kingdom | |
NHS Lothian, Western General Hospital | |
Edinburgh, United Kingdom, EH4 2XU | |
Princess Alexandra Hospital | |
Harlow, United Kingdom, CM201QX | |
Northumbria Healthcare NHS Foundation Trust | |
North Shields, United Kingdom, NE29 8NH | |
Warrington and Halton Hospitals Nhs Foundation Trust | |
Warrington, United Kingdom, WA5 1QG |
Study Director: | Galapagos Study Director | Gilead Sciences |
Responsible Party: | Galapagos NV |
ClinicalTrials.gov Identifier: | NCT03025308 |
Other Study ID Numbers: |
GS-US-417-0304 2016-003630-25 ( EudraCT Number ) |
First Posted: | January 19, 2017 Key Record Dates |
Last Update Posted: | October 21, 2022 |
Last Verified: | October 2022 |
Studies a U.S. FDA-regulated Drug Product: | Yes |
Studies a U.S. FDA-regulated Device Product: | No |
Arthritis Arthritis, Rheumatoid Joint Diseases Musculoskeletal Diseases |
Rheumatic Diseases Connective Tissue Diseases Autoimmune Diseases Immune System Diseases |