COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC:

Get the latest research information from NIH: Menu

Subclinical Hypothyroidism and Acute Anterior Myocardial Infarction: Is it Cardio-protective or Not?

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT03017157
Recruitment Status : Unknown
Verified January 2017 by Hillel Yaffe Medical Center.
Recruitment status was:  Not yet recruiting
First Posted : January 11, 2017
Last Update Posted : January 11, 2017
Information provided by (Responsible Party):
Hillel Yaffe Medical Center

Brief Summary:
The study plans to investigate whether recovery of the heart function after acute anterior myocardial infarction is dependent upon improvement in thyroid gland functioning.

Condition or disease Intervention/treatment
Heart Injuries Other: Echo-cardiogram Other: Blood test

Layout table for study information
Study Type : Observational
Estimated Enrollment : 50 participants
Observational Model: Cohort
Time Perspective: Prospective
Study Start Date : January 2017
Estimated Primary Completion Date : April 2017
Estimated Study Completion Date : April 2017

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Heart Attack

Group/Cohort Intervention/treatment
Anterior Myocardial Infarction
Patients who have suffered anterior myocardial infarction in our hospital
Other: Echo-cardiogram
Patients will undergo echo-cardiogram to determine improvement in their heart function and this will be compared to thyroid function

Other: Blood test
Blood test to determine thyroid function

Primary Outcome Measures :
  1. Ejection Fraction Improvement [ Time Frame: 40 days ]
    Improvement in ejection fraction as shown in echo-cardiogram

  2. Improvement in thyroid function [ Time Frame: 40 days ]
    Thyroid stimulating hormone (TSH) level will be normal.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Patients who have suffered anterior myocardial infarction who have been hospitalized in our hospital's cardiac unit.

Inclusion Criteria:

  • Have suffered anterior myocardial infarction

Exclusion Criteria:

  • Do not receive thyroid treatment
  • No history of ischemic heart disease

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT03017157

Layout table for location contacts
Contact: Rami Abo Fane, MD, PhD

Layout table for location information
Hillel Yaffe Medical Center
Hadera, Israel, 38100
Contact: Rami Abo Fane, MD, PhD   
Principal Investigator: Rami Abo Fane, MD, PhD         
Sponsors and Collaborators
Hillel Yaffe Medical Center
Layout table for additonal information
Responsible Party: Hillel Yaffe Medical Center Identifier: NCT03017157    
Other Study ID Numbers: 0096-16-HYMC
First Posted: January 11, 2017    Key Record Dates
Last Update Posted: January 11, 2017
Last Verified: January 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No
Additional relevant MeSH terms:
Layout table for MeSH terms
Heart Injuries
Thoracic Injuries
Wounds and Injuries