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The Effects of Two Induction Means on Emergence After General Anesthesia

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ClinicalTrials.gov Identifier: NCT02974712
Recruitment Status : Not yet recruiting
First Posted : November 28, 2016
Last Update Posted : November 28, 2016
Sponsor:
Information provided by (Responsible Party):
RenJi Hospital

Brief Summary:
This study aims to investigate the effects of different methods of administration on emergence period after laryngeal mask anesthesia in elderly patients undergoing transurethral endoscopic operation

Condition or disease Intervention/treatment Phase
Mean Arterial Pressure Heart Rate Drug: Fentanyl Drug: Saline Not Applicable

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 60 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Outcomes Assessor)
Primary Purpose: Prevention
Official Title: The Effects of Two Induction Means on Emergence After General Anesthesia for Elderly Patients Undergoing Transurethral Endoscopic Operation
Study Start Date : December 2016
Estimated Primary Completion Date : March 2017
Estimated Study Completion Date : March 2017

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: Fentanyl
After routine Induction, fentanyl was administrated.
Drug: Fentanyl
Placebo Comparator: Saline
After routine Induction, same volume saline was administrated.
Drug: Saline



Primary Outcome Measures :
  1. Mean arterial pressure (MAP) [ Time Frame: One hour after surgery ]

Secondary Outcome Measures :
  1. Lengths of stays in the Post anesthesia care unit(PACU) [ Time Frame: One hour after surgery ]


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Ages Eligible for Study:   65 Years to 79 Years   (Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • ASA level I or II,
  • Aged from 65 to 79,
  • With a duration of anesthesia <90 min.

Exclusion Criteria:

  • Chronic obstructive pulmonary diseases (COPD),
  • Severe heart disease,
  • Difficult airway
  • Liver and kidney dysfunction,
  • Cerebrovascular disease,
  • Bleeding volume >20 ml.

Responsible Party: RenJi Hospital
ClinicalTrials.gov Identifier: NCT02974712     History of Changes
Other Study ID Numbers: 20161114
First Posted: November 28, 2016    Key Record Dates
Last Update Posted: November 28, 2016
Last Verified: November 2016

Keywords provided by RenJi Hospital:
Arterial blood gases
MAP
HR

Additional relevant MeSH terms:
Fentanyl
Analgesics, Opioid
Narcotics
Central Nervous System Depressants
Physiological Effects of Drugs
Analgesics
Sensory System Agents
Peripheral Nervous System Agents
Adjuvants, Anesthesia
Anesthetics, Intravenous
Anesthetics, General
Anesthetics