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Dresden Glaucoma and Treatment Study (DGTS)

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ClinicalTrials.gov Identifier: NCT02959242
Recruitment Status : Recruiting
First Posted : November 9, 2016
Last Update Posted : February 23, 2021
Sponsor:
Information provided by (Responsible Party):
Dr. Karin Pillunat, Technische Universität Dresden

Brief Summary:
To assure the quality of follow-up and treatment, data of glaucoma patients are stored and evaluated after anonymisation.

Condition or disease
Glaucoma Glaucoma, Open-Angle Glaucoma, Angle-Closure Glaucoma, Low Tension

Detailed Description:

The aim of the study is to evaluate the quality of follow-up and treatment by means of consecutive data collection and anonymised analysis of all glaucoma patients of a tertiary university hospital glaucoma service.

Parameters being analyzed are:

Age, sex, refraction, family history, known duration of glaucoma, highest intraocular pressure before treatment, systemic and topical medication, previous ocular surgery.

24h Goldmann-applanation tonometry, biomicroscopy, gonioscopy, Heidelberg Retinal Tomograph (HRT), glaucoma diagnosis with Scanning-Laser-Polarimetry (GDx), optical coherence tomography (OCT), Pentacam, Ocular Response Analyzer (ORA), Corvis ST (Corneal Visualization with the Scheimpflug Technology), perimetry

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Study Type : Observational
Estimated Enrollment : 10000 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Dresden Glaucoma and Treatment Study: Analysis to Assure the Quality of Follow-up and Therapy of Glaucoma Patients in a Tertiary University Hospital Glaucoma Service.
Study Start Date : January 2006
Estimated Primary Completion Date : December 2026
Estimated Study Completion Date : December 2026

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Glaucoma




Primary Outcome Measures :
  1. Follow-up intervals [ Time Frame: 20 years ]
    To find the best follow-up intervals for glaucoma patients.


Secondary Outcome Measures :
  1. Assessment of treatment quality [ Time Frame: 20 years ]
    What is the best treatment option for the individual patient?

  2. Assessment of intraocular pressure-lowering efficacy and number of participants with treatment-related adverse events as assessed by CTCAE v4.0 of glaucoma laser therapy [ Time Frame: 20 years ]
    Diurnal intraocular pressure, best corrected visual acuity, visual fields

  3. Assessment of intraocular pressure-lowering efficacy and number of participants with treatment-related adverse events as assessed by CTCAE v4.0 of glaucoma laser therapy of glaucoma surgery [ Time Frame: 20 years ]
    Diurnal intraocular pressure, best corrected visual acuity, visual fields



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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Glaucoma patients attending a tertiary University Hospital glaucoma Service.
Criteria

Inclusion Criteria:

  • manifest glaucoma, ocular Hypertension, glaucoma suspect

Exclusion Criteria:

  • under 18 years of age, corneal diseases

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02959242


Contacts
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Contact: Karin R Pillunat, MD +49 351 458 3274 karin.pillunat@uniklinikum-dresden.de
Contact: Lutz E Pillunat, MD, PhD +49 351 458 3381 lutze.pillunat@uniklinikum-dresden.de

Locations
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Germany
University Eye Hospital, Medical Faculty, Technical University Dresden Recruiting
Dresden, Saxony, Germany, 01307
Contact: Karin R Pillunat, MD    +49 351 458 ext 3274    karin.pillunat@uniklinikum-dresden.de   
Contact: Lutz E Pillunat, MD, PhD    +49 351 458 ext 3381    lutze.pillunat@uniklinikum-dresden.de   
Sponsors and Collaborators
Technische Universität Dresden
Investigators
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Study Director: Lutz E Pillunat, MD, PhD Medical faculty of the Technical University of Dresden, Germany
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Responsible Party: Dr. Karin Pillunat, Dr. med., Technische Universität Dresden
ClinicalTrials.gov Identifier: NCT02959242    
Other Study ID Numbers: DGTS
First Posted: November 9, 2016    Key Record Dates
Last Update Posted: February 23, 2021
Last Verified: February 2021
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No
Plan Description: Individual participant data are only shared between researchers of our Institute.
Keywords provided by Dr. Karin Pillunat, Technische Universität Dresden:
Follow-up intervals
Treatment Efficiency
Laser Therapy
Glaucoma Surgery
Minimal Invasive Glaucoma Surgery (MIGS)
Additional relevant MeSH terms:
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Glaucoma
Glaucoma, Open-Angle
Glaucoma, Angle-Closure
Low Tension Glaucoma
Ocular Hypertension
Eye Diseases
Optic Nerve Diseases