Association of Snowfall and Myocardial Infarction
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|ClinicalTrials.gov Identifier: NCT02913820|
Recruitment Status : Completed
First Posted : September 26, 2016
Last Update Posted : January 10, 2018
|Condition or disease||Intervention/treatment|
|Acute Myocardial Infarction||Other: snowfall > 5cm/day|
Besides classical cardiovascular risk factors such as smoking, obesity, elevated cholesterol levels and diabetes there are also acute factors potentially triggering acute coronary events. The impact of air temperature (changes) or humidity are of potential relevance. In addition, exercise and the associated increase in oxygen demand of the myocardium and blood pressure is another trigger for plaque rupture and the acute onset of myocardial infarction. Male patients as well as patients with previous coronary heart disease or little regular exercise are at increased risk.
Possible additional mechanisms of exercise induced myocardial infarction are vasospasm and changes in blood clotting.
Changes in the ambient temperature (warm to cold) can also induce vasospasm which might result in reduced perfusion and plaque rupture. It seems that male patients are more involved than female patients.
Taking the exercise and the ambient temperature changes into consideration, heavy snowfall with consecutive snow shoveling is an augmented risk for acute myocardial infarction.
The rationale of the study is to test if the above mentioned constellation of environmental factors as well as potential increased exercise have a significant and independent impact on the incidence of myocardial infarctions
|Study Type :||Observational|
|Actual Enrollment :||18075 participants|
|Official Title:||Association of Snowfall and Myocardial Infarction|
|Study Start Date :||January 2007|
|Actual Primary Completion Date :||June 30, 2017|
|Actual Study Completion Date :||June 30, 2017|
impact of snowfall and its correlation with acute myocardial infarctions is analyzed. Other precipitation (rainfall) changes in atmospheric pressure and temperature will be variables to be corrected for.
Other: snowfall > 5cm/day
the number of myocardial infarctions of every day analysed in this study will be correlated with the respective values of snowfall
- myocardial infarction [ Time Frame: 1 day ]the number of myocardial infarctions of every day analysed in this study will be correlated with the respective values of snowfall
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02913820
|Medical University of Graz|
|Graz, Austria, 8010|