Individualized Lung Recruitment Maneuver Guide by Pulse-oximetry in Anesthetized Patients
|ClinicalTrials.gov Identifier: NCT02912819|
Recruitment Status : Completed
First Posted : September 23, 2016
Last Update Posted : September 23, 2016
General anesthesia and mechanical ventilation promotes atelectasis and airway closure. The open-lung approach (OLA) strategy restores the functional residual capacity. Pulse oximetry hemoglobin saturation (SpO2) using room air can diagnose shunt induced by lung collapse during general anesthesia and the SpO2 breathing air was useful to detect the lung´s opening and closing pressure during a recruitment maneuver (RM) in morbidly obese anesthetized patients.
Investigators hypothesized that the SpO2 breathing air can personalize the open-lung approach.
|Condition or disease||Intervention/treatment|
|Abdominal Cancer||Other: Open-lung approach|
|Study Type :||Observational|
|Actual Enrollment :||30 participants|
|Official Title:||Individualized Lung Recruitment Maneuver Guide by Pulse-oximetry in Anesthetized Patients|
|Study Start Date :||January 2016|
|Actual Primary Completion Date :||July 2016|
|Actual Study Completion Date :||August 2016|
- Other: Open-lung approach
Increase and decrease in airway pressure to open the lung and keep them opened.
- open-lung condition [ Time Frame: During the experimental protocol (Intraoperative) ]The role of the SpO2 to detect lung´s closing and opening pressures was evaluated by the discrete receiver operating characteristic (ROC) analysis. With PtpEE and PaO2/FIO2 as the reference methods, a binary classification of "1" to the open-lung condition defined as positive PtpEE or PaO2/FIO2 >400 mmHg and "0" presence of lung collapse defined as negative PtpEE or PaO2/FIO2 <400 mmHg. Also, a value of "1" was assigned when the SpO2 was ≥ 97% and a value of "0" when the value was < 97%.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02912819
|Department of Anesthesia and Critical Care; Hospital Clinico Universitario|
|Valencia, Spain, 46010|