Fetal Renal Artery Doppler Indices in Borderline Isolated Oligohydramnios
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|ClinicalTrials.gov Identifier: NCT02901340|
Recruitment Status : Unknown
Verified September 2016 by Erdem Sahin, Kayseri Education and Research Hospital.
Recruitment status was: Recruiting
First Posted : September 15, 2016
Last Update Posted : September 15, 2016
|Condition or disease||Intervention/treatment|
|Oligohydramnios||Dietary Supplement: one to two liters of water daily|
During a routine pregnancy examination at 34-37 weeks gestation, the fetus was evaluated using ultrasound with the Toshiba Xario 200 3.5-megahertz probe. Fetal biometric measurements were obtained and placental structure and the amniotic fluid amount were evaluated in four quadrants. After detailed ultrasonography of the fetus, eligible pregnant women were included in the study.
Borderline idiopathic isolated oligohydramnios was defined according to the four quadrants technical with ultrasound examination and diagnosed with amniotic fluid index >5.0 and ≤8.0cm. After first ultrasound examination all patients in borderline isolated oligohydramnios group were hydrated with one to two liters of water daily. All patients monitored with non stress test and amniotic fluid index twice weekly until delivery after treatment with hydration.
For evaluating renal artery blood flow, an axial image of the fetal abdomen was obtained at the level of the fetal kidneys. Using color flow Doppler, the renal arteries were evaluated at the level of their origin from the abdominal aorta. The Doppler gate was placed within the lumen in a straight segment of the vessel. A minimum of three consecutive waveforms was used to calculate the PI. The umbilical artery Doppler measurements were studied in a free loop of cord, far from the fetus and placenta. pulsatile index and resistance index values were recorded.
The study consisted of two groups. The first group was formed of the patients who had normal amniotic volume and meets the inclusion criteria. In second group the investigators included patients who diagnosed borderline idiopathic isolated oligohydramnios. After delivery the investigators compared fetal renal artery doppler indices and neonatal outcomes between groups.
|Study Type :||Observational|
|Estimated Enrollment :||140 participants|
|Observational Model:||Case Control|
|Official Title:||Third Trimester Fetal Renal Artery Doppler Indices in Borderline Idiopathic Isolated Oligohydramnios and Relationship Between Neonatal Outcomes|
|Study Start Date :||August 2016|
|Estimated Primary Completion Date :||December 2016|
|Estimated Study Completion Date :||December 2016|
Borderline isolated oligohydramnios
Borderline idiopathic isolated oligohydramnios was defined according to the four quadrants technical with ultrasound examination and diagnosed with amniotic fluid index>5.0 and ≤8.0cm.
The borderline idiopathic isolated oligohydramnios group was formed of the patients who meets the inclusion criteria and between 34-37 weeks gestation (n:40)
Dietary Supplement: one to two liters of water daily
The control group was formed of the patients who had normal amniotic volume and 34-37 weeks gestation who meets the inclusion criteria (n:100)
- Fetal renal artery pulsatile index in borderline idiopathic isolated oligohydramnios [ Time Frame: 4 months ]
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02901340
|Contact: Erdem SAHİN, Study Principal İnvestigatorfirstname.lastname@example.org|
|Kayseri Training and Research Hospital||Recruiting|
|Kayseri, Turkey, 38000|