Working…
Help guide our efforts to modernize ClinicalTrials.gov.
Send us your comments by March 14, 2020.
ClinicalTrials.gov
ClinicalTrials.gov Menu

Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT02898480
Recruitment Status : Completed
First Posted : September 13, 2016
Last Update Posted : April 5, 2019
Sponsor:
Information provided by (Responsible Party):
University of Aarhus

Brief Summary:
Remote ischemic conditioning (RIC) is a therapeutic strategy for protecting organs or tissue against the detrimental effects of acute ischemia-reperfusion injury. It remains unknown whether this can be used in retinal vascular occlusive diseases. The purpose of the present study is to examine whether the autoregulation of retinal vessel diameters in normal persons change after remote ischemic conditioning.

Condition or disease Intervention/treatment Phase
Retinal Artery Occlusion Retinal Vein Occlusion Procedure: Remote ischemic conditioning Not Applicable

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 20 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Basic Science
Official Title: Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning
Study Start Date : September 2016
Actual Primary Completion Date : November 14, 2016
Actual Study Completion Date : May 2017

Arm Intervention/treatment
Experimental: Remote ischemic conditioning Procedure: Remote ischemic conditioning
Briefly reversible restricting of blood flow to upper limb in four cycles of 5 minutes of inflation at 200mm Hg followed by 5 minutes of deflation.




Primary Outcome Measures :
  1. Diameter change of retinal vessel [ Time Frame: immediate ]


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   20 Years to 35 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Normal persons

Exclusion Criteria:

  • Present or previous eye disease
  • Use of medications except anti-conceptive
  • Epilepsy
  • Pregnancy or lactation

Layout table for additonal information
Responsible Party: University of Aarhus
ClinicalTrials.gov Identifier: NCT02898480    
Other Study ID Numbers: RIK-DVA
First Posted: September 13, 2016    Key Record Dates
Last Update Posted: April 5, 2019
Last Verified: November 2017
Additional relevant MeSH terms:
Layout table for MeSH terms
Retinal Vein Occlusion
Retinal Artery Occlusion
Retinal Diseases
Eye Diseases
Venous Thrombosis
Thrombosis
Embolism and Thrombosis
Vascular Diseases
Cardiovascular Diseases
Arterial Occlusive Diseases