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Locally Applied Pressure-induced Vasodilatation (LAV)

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ClinicalTrials.gov Identifier: NCT02861924
Recruitment Status : Completed
First Posted : August 10, 2016
Last Update Posted : November 7, 2019
Sponsor:
Information provided by (Responsible Party):
University Hospital, Angers

Brief Summary:
Measure microcirculatory responses after localized ischemia obtained by local application of pressure (laser speckle).

Condition or disease Intervention/treatment Phase
Vascular Diseases Other: microcirculatory responses Not Applicable

Detailed Description:

Measure microcirculatory responses after localized ischemia obtained by local application of pressure (laser speckle). The purpose of this study is to perform measurements of the methodological points made.

The study will investigate :

  • The effect of the duration and intensity of the pressure
  • The reproducibility of measurements
  • The correlation with ischemic hyperemia post

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 45 participants
Allocation: N/A
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: Réponse à l'Application d'Une Pression Locale en Laser Speckle Imaging Locally Applied Pressure-induced Vasodilatation
Actual Study Start Date : October 11, 2016
Actual Primary Completion Date : March 31, 2017
Actual Study Completion Date : March 31, 2019

Arm Intervention/treatment
Experimental: microcirculatory responses

Measure microcirculatory responses after localized ischemia obtained by local application of pressure (laser speckle).

A pressure is applied to the subject's arm. this causes a localized ischemia. the measures responses to this ischemia will be made by the imager speckle (LSCI) give the microvascular perfusion data.

Other: microcirculatory responses

The effect of the duration and intensity of the pressure; reproducibility and correlation with ischemic hyperemia post.

measurements are made with the Imager SPECKLE imager (LSCI) give the microvascular perfusion data in arbitrary units called perfusion units (UP).





Primary Outcome Measures :
  1. microcirculatory response to local pressure. Measurements are made with the Imager SPECKLE imager (LSCI) give the microvascular perfusion data in arbitrary units called perfusion units (UP). [ Time Frame: 2 hours ]
    Measurements are made with the Imager SPECKLE imager (LSCI) give the microvascular perfusion data in arbitrary units called perfusion units (UP).



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • subjects without vascular pathology

Exclusion Criteria:

  • pregnancy
  • allergy tape

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02861924


Locations
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France
CHU Angers
Angers, France, 49933
Sponsors and Collaborators
University Hospital, Angers
Investigators
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Principal Investigator: Pierre ABRAHAM, professor UH ANGERS
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
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Responsible Party: University Hospital, Angers
ClinicalTrials.gov Identifier: NCT02861924    
Other Study ID Numbers: 2016-A00609-42
First Posted: August 10, 2016    Key Record Dates
Last Update Posted: November 7, 2019
Last Verified: November 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No
Additional relevant MeSH terms:
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Vascular Diseases
Cardiovascular Diseases