Transcranial Direct Current Stimulation (TDCS) as an Intervention for Patients With Traumatic Brain Injury
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|ClinicalTrials.gov Identifier: NCT02849223|
Recruitment Status : Active, not recruiting
First Posted : July 29, 2016
Last Update Posted : February 20, 2020
|Condition or disease||Intervention/treatment||Phase|
|Traumatic Brain Injury||Device: Anodal Transcranial Direct Current Stimulation Device: Sham stimulation||Phase 2|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||41 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Outcomes Assessor)|
|Official Title:||Transcranial Direct Current Stimulation (TDCS) as an Intervention for Patients With Traumatic Brain Injury|
|Actual Study Start Date :||July 2016|
|Estimated Primary Completion Date :||January 2021|
|Estimated Study Completion Date :||January 2021|
Experimental: Transcranial Direct Current Stimulation
Participants will receive 24 sessions (3 times a week) of anodal transcranial direct current stimulation concurrent with working memory training. Stimulation will be administered at 2 milliamps (mA) for 20 minutes over the left dorsal lateral prefrontal cortex.
Device: Anodal Transcranial Direct Current Stimulation
2 milliamps (mA) of anodal stimulation will be applied to the left dorsal lateral cortex for 20 minutes concurrent with working memory training.
Sham Comparator: Sham
Participants will receive 24 sessions of working memory training. The experience of transcranial direct current stimulation will be simulated by administering 30 seconds of stimulation at the beginning of the session.
Device: Sham stimulation
30 seconds of anodal TDCS stimulation will be applied to the left dorsal lateral cortex concurrent with working memory training
- Wechsler Adult Intelligence Scale (WAIS)-III Working Memory Index [ Time Frame: Post-Intervention, 9-10 weeks after baseline assessment ]Standard score
- University of California Performance Based Skills Assessment [ Time Frame: Post-Intervention, 9-10 weeks after baseline assessment ]Total Score
- Resting state electroencephalogram (EEG) [ Time Frame: Post-Intervention, 8-9 weeks after baseline assessment ]Theta amplified oscillatory power
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02849223
|United States, Minnesota|
|Minneapolis Veterans Affairs Health Care System|
|Minneapolis, Minnesota, United States, 55417|
|Principal Investigator:||Tasha M Nienow, PhD||Minneapolis Veteran Affairs Health Care System|