Working…
ClinicalTrials.gov
ClinicalTrials.gov Menu
Help guide our efforts to modernize ClinicalTrials.gov.
Send us your comments by March 14, 2020.

The Role of Expectations in Experimentally Induced Sadness

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT02848352
Recruitment Status : Completed
First Posted : July 28, 2016
Last Update Posted : April 6, 2017
Sponsor:
Information provided by (Responsible Party):
Winfried Rief, Philipps University Marburg Medical Center

Brief Summary:
The study aimed at identifying whether different expectations have an impact on experiencing emotions in the form of sadness.

Condition or disease Intervention/treatment Phase
Healthy Participants Other: Placebo nasal spray Other: Film Sequence Not Applicable

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 128 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Care Provider, Investigator)
Primary Purpose: Basic Science
Official Title: The Role of Expectations in Experimentally Induced Sadness
Study Start Date : June 2016
Actual Primary Completion Date : October 2016
Actual Study Completion Date : October 2016

Arm Intervention/treatment
Experimental: Positive placebo group
Participants receive a nasal spray that is a placebo. However, they are told that it protects from experiencing negative emotions. Participants watch a film sequence that is supposed to induce sadness.
Other: Placebo nasal spray
Other: Film Sequence
Experimental: Negative placebo group
Participants receive a nasal spray that is a placebo. However, they are told that it sensitizes for experiencing negative emotions. Participants watch a film sequence that is supposed to induce sadness.
Other: Placebo nasal spray
Other: Film Sequence
Placebo Comparator: Placebo control group
Participants receive a nasal spray that is a placebo and are told that it is a placebo. Participants watch a film sequence that is supposed to induce sadness.
Other: Placebo nasal spray
Other: Film Sequence
No-treatment control group
Participants do not receive the nasal spray. Participants watch a film sequence that is supposed to induce sadness.
Other: Film Sequence



Primary Outcome Measures :
  1. Sadness (PANAS-X) [ Time Frame: Directly after watching the film sequence, no follow-up assessments ]


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   18 Years to 40 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • fluent in German language

Exclusion Criteria:

  • major depression
  • current intake of psychotropic medication
  • drug intake within the last two weeks
  • alcohol consumption within the last twelve hours
  • allergic to capsaicin
  • allergic to sesame oil
  • students in medicine, pharmacy, or psychology in their third year or older

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02848352


Locations
Layout table for location information
Germany
Philipps University Marburg
Marburg, Hessen, Germany, 35037
Sponsors and Collaborators
Philipps University Marburg Medical Center
Investigators
Layout table for investigator information
Principal Investigator: Winfried Rief, Professor Philipps University Marburg Medical Center

Layout table for additonal information
Responsible Party: Winfried Rief, Professor Dr., Philipps University Marburg Medical Center
ClinicalTrials.gov Identifier: NCT02848352    
Other Study ID Numbers: 2016-02v
First Posted: July 28, 2016    Key Record Dates
Last Update Posted: April 6, 2017
Last Verified: July 2016
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No