Study of Fecal Bacteria in Early Diagnosis of Colorectal Cancer
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|ClinicalTrials.gov Identifier: NCT02845973|
Recruitment Status : Unknown
Verified July 2016 by Jing-yuan Fang, MD, Ph. D, Shanghai Jiao Tong University School of Medicine.
Recruitment status was: Recruiting
First Posted : July 27, 2016
Last Update Posted : July 27, 2016
|Condition or disease||Intervention/treatment|
|Colorectal Neoplasms||Biological: gut microbiota|
|Study Type :||Observational|
|Estimated Enrollment :||1000 participants|
|Study Start Date :||June 2016|
|Estimated Primary Completion Date :||September 2016|
|Estimated Study Completion Date :||December 2016|
cohort includes patients with and without colorectal neoplasia from 2011.6 through 2016.1 who are over 40 years old and have a valid CEA(carcino embryonic antigen) and OB(occult blood) test results, as well as a valid coloscopy. The constitution of gut microbiota for each group will be studied and compared to establish a new diagnosis model for colorectal cancer.
Biological: gut microbiota
cohort includes patients with and without colorectal neoplasia from 2016.2 through 2016.9 who are over 40 years old and have a valid CEA(carcino embryonic antigen) and OB(occult blood) test results. The constitution of gut microbiota for each group will be studied and compared following by a coloscopy to verify the diagnosis model.
Biological: gut microbiota
- differences in abundance of gut microbiota [ Time Frame: 1 year ]differences in abundance of gut microbiota for participants with different clinical outcomes confirmed by qPCR(quantitive polymerase chain reaction)
- evidence of colorectal neoplasia [ Time Frame: 1 year ]Different outcomes for colorectal neoplasia confirmed by coloscopy
- diet difference in patients with different clinical outcomes [ Time Frame: 1 year ]Diet difference in patients with different clinical outcomes by a food-frequency questionnaire
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02845973
|Contact: Jingyuan Fang, MD. Ph.Dfirstname.lastname@example.org|
|Shanghai Institute of Digestive Disease||Recruiting|
|Shanghai, China, 200001|
|Principal Investigator: jing-yuan Fang, MD. Ph D.|