A Study of Gene Polymorphisms Associated With Specific Presentations of Sexual Addiction
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| ClinicalTrials.gov Identifier: NCT02844985 |
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Recruitment Status
:
Recruiting
First Posted
: July 26, 2016
Last Update Posted
: August 8, 2017
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Sponsor:
American Foundation for Addiction Research
Collaborators:
University of Alberta
University of Southern Mississippi
Information provided by (Responsible Party):
American Foundation for Addiction Research
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Brief Summary:
The study is intended to identify gene polymorphisms significantly associated with specific behavioral- and preoccupation-typologies of sexual addiction, and to identify additional potential genetic markers of sexual addiction. Research subjects with sexual addiction will be identified from the out-patient and in-patient populations of the investigative sites. Research subjects in the Control Group will be identified from the general population and from the student body of selected colleges. Approximately 1100 subjects will be enrolled in the study. Anticipating 10% drop-out, this is intended to generate a population of approximately 500 men and women clinically diagnosed with sexual addiction, and approximately 500 healthy men and women who do not meet diagnostic criteria for sexual addiction nor have psychopathology who will serve as the control population.
| Condition or disease | Intervention/treatment |
|---|---|
| Sexual Addiction | Other: No Intervention |
| Study Type : | Observational |
| Estimated Enrollment : | 1100 participants |
| Observational Model: | Case-Control |
| Time Perspective: | Cross-Sectional |
| Official Title: | Genetic Markers in Sexual Addiction |
| Actual Study Start Date : | August 17, 2016 |
| Estimated Primary Completion Date : | June 2018 |
| Estimated Study Completion Date : | June 2018 |
Resource links provided by the National Library of Medicine
MedlinePlus related topics:
Genes and Gene Therapy
U.S. FDA Resources
| Group/Cohort | Intervention/treatment |
|---|---|
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Addict Group
In-patient and out-patient adult men and women who meet diagnostic criteria for sexual addiction.
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Other: No Intervention |
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Control Group
Individuals from the general community and college student populations who have no history of identifiable psychopathology.
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Other: No Intervention |
Primary Outcome Measures
:
- Gene polymorphisms identified through polymerase chain reaction using fluorescent primers and restriction fragment length polymorphism analysis [ Time Frame: Assessed at Enrollment ]
Biospecimen Retention: Samples With DNA
Saliva specimens will be collected from all participants for genetic evaluation.
Information from the National Library of Medicine
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
| Ages Eligible for Study: | 18 Years and older (Adult, Senior) |
| Sexes Eligible for Study: | All |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Study Population
Sexual Addict Group: individuals undergoing treatment for sexual addiction.
Control Group: individuals from general community who have no history of addiction or psychopathology
Criteria
Inclusion Criteria:
- Sexual Addict Group
Age >= 18 years
Participating in sexual addiction treatment program
Sexual Addiction Screening Test--Revised (SAST-R) score >= 11
Meets at least 3 diagnostic criteria for sexual addiction
- Control Group
Age >= 18 years
SAST-R score < 6
Exclusion Criteria:
- Sexual Addiction Group
Serious mental illness
Significant cognitive impairment
- Control Group
History of addiction
Current or previous Diagnostic and Statistical Manual (DSM-5) diagnosis
Serious mental illness
Significant cognitive impairment
Information from the National Library of Medicine
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02844985
Contacts
| Contact: Executive Director | 480-488-7053 | study@addictionresearch.com |
Locations
| United States, Arizona | |
| Psychological Counseling Services | Recruiting |
| Scottsdale, Arizona, United States, 85251 | |
| Contact: Richard Isenberg, MD 480-947-5739 rick.isenberg.md@pcsearle.com | |
| Principal Investigator: Richard A Isenberg, MD | |
| Gentle Path at The Meadows | Recruiting |
| Wickenburg, Arizona, United States, 85390 | |
| Contact: Isabel de Guzman, PhD 928-684-4080 ideguzman@gentlepathmeadows.com | |
| Sub-Investigator: Isabel de Guzman, PhD | |
| Principal Investigator: Patrick Carnes, PhD | |
| United States, California | |
| Center for Healthy Sex | Recruiting |
| Los Angeles, California, United States, 90025 | |
| Contact: Piper Grant, PhD 310-843-9902 piper@centerforhealthysex.com | |
| Principal Investigator: Alexandra Katehakis, MFT | |
| Triune Therapy Group | Recruiting |
| Los Angeles, California, United States, 90025 | |
| Contact: Kate Balestrieri, PsyD 310-933-4088 kate@triunetherapy.com | |
| Principal Investigator: Kate Balestrieri, PsyD | |
| United States, Mississippi | |
| Pine Grove Behavioral Health and Addiction Services | Recruiting |
| Hattiesburg, Mississippi, United States, 39402 | |
| Contact: Gregory L Futral, PhD 601-288-4999 gfutral@forrestgeneral.com | |
| Principal Investigator: Gregory L Futral, PhD | |
| United States, New York | |
| Kavod Center | Recruiting |
| Rochester, New York, United States, 14607 | |
| Contact: Michelle Laugh, MS 585-546-5180 morris@rpa.net | |
| Principal Investigator: Daniel A MORRIS, LCSW | |
| United States, Texas | |
| Center for Healthy Sexuality | Recruiting |
| Houston, Texas, United States, 77057 | |
| Contact: Mark Bourliea 713-785-7111 | |
| Principal Investigator: Barbara Levinson, PhD | |
| United States, Washington | |
| Seattle Christian Counseling | Recruiting |
| Bellevue, Washington, United States, 98004 | |
| Contact: Chris Chandler, LMHC 425-289-9589 chris@seattlechristiancounseling.com | |
| Principal Investigator: Christopher Chandler, LMHC | |
Sponsors and Collaborators
American Foundation for Addiction Research
University of Alberta
University of Southern Mississippi
| Responsible Party: | American Foundation for Addiction Research |
| ClinicalTrials.gov Identifier: | NCT02844985 History of Changes |
| Other Study ID Numbers: |
AFAR 2016-001 |
| First Posted: | July 26, 2016 Key Record Dates |
| Last Update Posted: | August 8, 2017 |
| Last Verified: | August 2017 |
| Individual Participant Data (IPD) Sharing Statement: | |
| Plan to Share IPD: | No |
Keywords provided by American Foundation for Addiction Research:
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Sexual Addiction Genomics Personality Polymorphism |
Additional relevant MeSH terms:
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Behavior, Addictive Compulsive Behavior Impulsive Behavior |