Comparison of Analgesic Effect of Volatile Anesthetics
|ClinicalTrials.gov Identifier: NCT02830243|
Recruitment Status : Completed
First Posted : July 12, 2016
Last Update Posted : May 15, 2018
|Condition or disease||Intervention/treatment||Phase|
|Anesthesia||Drug: Sevoflurane Drug: Desflurane||Phase 3|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||90 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Triple (Participant, Investigator, Outcomes Assessor)|
|Official Title:||The Comparison of Analgesic Effect of Volatile Anesthetics Using Surgical Pleth Index|
|Actual Study Start Date :||July 12, 2016|
|Actual Primary Completion Date :||October 5, 2016|
|Actual Study Completion Date :||October 8, 2016|
Anesthesia was maintained with sevoflurane.
End-tidal concentration of sevoflurane was maintained at age-corrected 1 minimum alveolar concentration throughout the study period. The remifentanil infusion rate was adjusted using TCI pump to achieve surgical pleth index between 20 and 50.
Other Name: SEVO
Anesthesia was maintained with desflurane.
End-tidal concentration of desflurane was maintained at age-corrected 1 minimum alveolar concentration throughout the study period. The remifentanil infusion rate was adjusted using TCI pump to achieve surgical pleth index between 20 and 50.
Other Name: DES
- Remifentanil consumption (µg/kg/min) [ Time Frame: During the intraoperative period ]
- Target effective site concentration of remifentanil (ng/ml) [ Time Frame: After at least 10 min of stable surgical pleth index values ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02830243
|Korea, Republic of|
|Kangbuk Samsung Hospital|
|Seoul, Korea, Republic of, 03181|
|Principal Investigator:||Kyoungho Ryu, M.D.||Kangbuk Samsung Hospital|