Vietnam Era Health Retrospective Observational Study (VE-HEROeS)
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|ClinicalTrials.gov Identifier: NCT02825602|
Recruitment Status : Unknown
Verified April 2019 by Victoria J. Davey PhD, MPH, Veteran Affairs Office of Patient Care Services.
Recruitment status was: Active, not recruiting
First Posted : July 7, 2016
Last Update Posted : April 24, 2019
The Vietnam Era Health Retrospective Observational Study (VE-HEROeS) is a national study on the health and well-being of Vietnam Veterans, including Blue Water Navy Veterans, as well as Veterans who served elsewhere during the Vietnam Era (1961-1975), and similarly aged U.S. residents who never served in the military. The investigators will invite approximately 43,000 Vietnam and Vietnam Era Veterans, and approximately 11,000 members of the general U.S. population to participate in VE-HEROeS. These individuals are scientifically selected to participate; the study is not able to accept volunteers.
All participants in VE-HEROeS will be asked to fill out a questionnaire on their military service, general health, age-related conditions, health care use, and the health experiences of their children and grandchildren. A smaller group will be asked to provide the investigators with access to some of their medical records. Topics of special focus for the study include cognition, hepatitis C infection, and neurologic conditions.
|Condition or disease|
|Aging Combat Disorders|
|Study Type :||Observational|
|Actual Enrollment :||24306 participants|
|Official Title:||Vietnam Era Health Retrospective Observational Study|
|Study Start Date :||July 2016|
|Actual Primary Completion Date :||March 31, 2017|
|Estimated Study Completion Date :||December 2019|
Vietnam War Theater Veterans
Vietnam War Theater Veterans are defined for this protocol as those who served in the U.S. Armed Forces on the ground, in the air, or on the inland waters of Vietnam, Cambodia, and/or Laos between February 28, 1961 and May 7, 1975, inclusive. The investigators based this definition on legal dates of service set forth in 38 Code of Federal Regulations (CFR) 3.2 - Periods of war, but broadened the definition of sites of military service that constituted war zones based on written historical accounts and input from Vietnam Veterans.
Blue Water Navy Vietnam Veterans
Blue Water Navy Veterans are defined as Veterans who served aboard deep-water naval vessels in waters offshore North or South Vietnam between February 28, 1961 and May 7, 1975 and who never served ashore or on inland waterways of Vietnam.
Vietnam era Veterans
Vietnam era Veterans served in locations around the world OTHER than on the ground, in the air, or on the inland waters of Vietnam, Cambodia, and/or Laos or aboard deep-water naval vessels in waters offshore North or South Vietnam between February 28, 1961 and May 7, 1975.
Non-military U.S. public
Non-military U.S. public are individuals who were born before 1958, never served in the U.S. military, and are age- and gender-matched (by the study investigators) to Vietnam War Theater Veterans.
- Overall Health [ Time Frame: Past 4 weeks ]Overall health will be measured by the mean physical component summary score (PCS) and the mean mental component score (MCS) of the Short Form 8 (SF-8) compared across the four groups. Mean scores on the 8 health concepts measured by the SF-8 (physical functioning, role limitations due to physical functioning, bodily pain, general health, energy/fatigue, social functioning, role limitations due to emotional problems, and psychological distress/well being) will also be compared. Adjustments may be made for age, gender, and prevalent co-morbidities.
- Conditions of concern [ Time Frame: Health history assessed at the time of survey (Day 1) ]The investigators will compare post-war prevalence of conditions that have been linked to Vietnam War service in other scientific studies of multiple designs: neurologic conditions ( Parkinson's disease, dementia, stroke, brain injury), Hepatitis C; hypertension, ischemic heart disease, Type II diabetes, peripheral neuropathy, various cancers, cirrhosis, alcohol and drug dependency.
- Self-identification of Blue Water Navy Vietnam Veterans [ Time Frame: Navy service exclusively in the deep offshore waters of Vietnam between February 28, 1961 and May 7, 1975. ]The investigators will ask Blue Water Navy Veterans to define themselves by their response to a survey question, as no roster of these Veterans exists.
- Health of offspring [ Time Frame: Health history assessed at the time of survey (Day 1) ]We ask survey respondents to report 9 conditions of their children and grandchildren that may be transmitted epigenetically
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02825602
|United States, District of Columbia|
|U.S. Department of Veterans Affairs/Epidemiology Program|
|Washington, District of Columbia, United States, 20420|
|Principal Investigator:||Victoria J Davey, PhD, MPH||US Department of Veterans Affairs|