Evaluation of Monitoring Neuromuscular Blockade the Flexor Hallucis Compared to the Adductor Pollicis (CurHaTOF)
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|ClinicalTrials.gov Identifier: NCT02825121|
Recruitment Status : Completed
First Posted : July 7, 2016
Last Update Posted : October 5, 2017
Current guidelines recommend monitoring of neuromuscular blockade at the adductor pollicis by stimulation of the ulnar nerve at the wrist.
However, in certain situations (laparoscopic surgery, cranial surgery or surgical comfort, arterial catheterization), it is impossible to access the patient's wrists, delaying monitoring, antagonizing the neuromuscular block, the emergence from anesthesia and patient extubation , leading in some cases to single injections lack of control of the reversal of the patient.
To overcome these technical difficulties, a group nerve / muscle looks interesting and often easily accessible to the anesthesiologist.
The stimulation of the posterior tibial nerve can observe a response to the flexor hallucis brevis muscle and allows quick access to monitoring the reversal before the end of the intervention.
The primary outcome was to compare the speed of recovery from neuromuscular block flexor hallux versus that of the adductor pollicis.
The secondary objective was to compare the speed of installation of deep neuromuscular block flexor hallucis versus that of the adductor pollicis.
This is a prospective, exploratory, uncontrolled, single-center for routine care.
Are included all aged patients over 18 years, ASA I or II, without guardianship, having no known allergy to Atracurium, without neuromyopathy known, emergency surgery or full stomach, predictable difficult intubation .
|Condition or disease||Intervention/treatment||Phase|
|Observation of Neuromuscular Block Flexor Hallucis Adductor Pollicis||Device: Monitoring Neuromuscular Blockade the Flexor Hallucis Device: Monitoring Neuromuscular Blockade adductor of the thumb.||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||60 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Study Start Date :||February 2016|
|Actual Primary Completion Date :||September 2017|
|Actual Study Completion Date :||September 2017|
Experimental: Monitoring Neuromuscular Blockade
Monitoring Neuromuscular Blockade the Flexor Hallucis and adductor of the thumb.
Device: Monitoring Neuromuscular Blockade the Flexor Hallucis
Device: Monitoring Neuromuscular Blockade adductor of the thumb.
- Time of occurrence of a T4 / T1 ratio> 0.90 in the train of four flexor hallucis [ Time Frame: 1 day ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02825121
|Poitiers Universitary Hospital|
|Poitiers, France, 86021|