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Troponin Leaks in Emergency Department Patients Presenting With Supraventricular Tachycardia (SVT)

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ClinicalTrials.gov Identifier: NCT02810561
Recruitment Status : Completed
First Posted : June 23, 2016
Last Update Posted : April 6, 2017
Sponsor:
Information provided by (Responsible Party):
Spectrum Health - Lakeland

Brief Summary:
The goal of this study is twofold. First the investigators would like to determine the trajectory of troponin leaks; if it can be shown that the participants who have only minimal elevations of their repeat troponin universally decrease on the 3rd level then future patients may see significantly improved length of stay. Second, given conflicting results in the literature, the investigators would like to determine if elevated troponin levels correlate to later cardiovascular complications. These complications will be defined as Death, Myocardial Infarction, Cardiovascular intervention (such as coronary artery stenting or bypass). As the investigator is a single hospital system in this county it is uniquely positioned to be able to review this retrospectively.

Condition or disease Intervention/treatment
Supraventricular Tachycardia Other: No Intervention

Detailed Description:
The investigators therefore propose retrospectively studying participants diagnosed with Supraventricular Tachycardia who had troponin(s) checked in the ED between January 1, 2012 and May 31, 2016 to allow a minimum of a year follow-up for our combined endpoint. The investigators will record the participants troponin value(s) in addition to the age, sex, race, heart rate, creatinine value. The investigators will compare the participants with positive troponins (and hopefully participants with strongly positive troponins) with those who are negative for troponin for presence of the combined end point via chart review.

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Study Type : Observational
Actual Enrollment : 63 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Time Course and the Significance of Troponin Leaks in Emergency Department Patients Presenting With Supraventricular Tachycardia (SVT)
Study Start Date : January 2012
Actual Primary Completion Date : July 2016
Actual Study Completion Date : July 2016

Intervention Details:
  • Other: No Intervention
    No intervention was completed with this study.


Primary Outcome Measures :
  1. Troponin-I Level [ Time Frame: 6 hours after initial EKG ]
    Measured in ng/ml


Secondary Outcome Measures :
  1. Death/ Need for Cardiac Stent Placement or Coronary Bypass Artery Graft [ Time Frame: 6 months ]


Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
All patients presenting to the Emergency Department with Supraventricular Tachycardia and elevated troponin. All sexs, races and ages will be included.
Criteria

Inclusion Criteria:

  • Supraventricular Tachycardia with troponin elevation

Exclusion Criteria:

  • Other cardiac arrhythmias or conditions with increased troponin

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02810561


Sponsors and Collaborators
Spectrum Health - Lakeland
Investigators
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Principal Investigator: Matthew Hysell, MD Lakeland Health Emergency Department
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Responsible Party: Spectrum Health - Lakeland
ClinicalTrials.gov Identifier: NCT02810561    
Other Study ID Numbers: LH01
First Posted: June 23, 2016    Key Record Dates
Last Update Posted: April 6, 2017
Last Verified: April 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided
Keywords provided by Spectrum Health - Lakeland:
Troponin
Additional relevant MeSH terms:
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Tachycardia
Tachycardia, Supraventricular
Emergencies
Disease Attributes
Pathologic Processes
Arrhythmias, Cardiac
Heart Diseases
Cardiovascular Diseases
Cardiac Conduction System Disease