Regenerative Endodontic Procedure of Immature Permanent Teeth With Apical Periodontitis Using PRF
|ClinicalTrials.gov Identifier: NCT02801552|
Recruitment Status : Unknown
Verified June 2016 by Xiaojing Huang, Fujian Medical University.
Recruitment status was: Recruiting
First Posted : June 16, 2016
Last Update Posted : June 17, 2016
|Condition or disease||Intervention/treatment||Phase|
|Periapical Periodontitis Tooth Diseases Stomatognathic Diseases||Device: PRF||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||50 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Single (Outcomes Assessor)|
|Official Title:||Regenerative Endodontic Procedure of Immature Permanent Teeth With Apical Periodontitis Using Platelet-rich Fibrin : A Pilot Randomized Controlled Trial|
|Study Start Date :||May 2013|
|Estimated Primary Completion Date :||November 2016|
|Estimated Study Completion Date :||February 2017|
Experimental: Regenerative Endodontic Procedure + PRF
Visit 1: root canal dressing with triple antibiotic paste. Visit 2: a 5 ml sample of whole blood was drawn intravenously from the patient's forearm. The blood sample is centrifuged at 400 g for 10 min. The prepared PRF membrane is cut into segments, the fragments are placed into the canal space. The coronal is sealed mineral trioxide aggregate and composite resin.
Regenerative Endodontic Procedure with PRF: autologous PRF will be used instead of blood clot in the second vist.
Other Name: mineral trioxide aggregate
No Intervention: Regenerative Endodontic Procedure
Regenerative Endodontic Procedure Visit 1: root canal dressing with triple antibiotic paste. Visit 2: Blood clot formation is induced in the root canal after disinfection. No PRF was used in this group. Then the canal access is sealed with mineral trioxide aggregate and composite resin.
- Evidence of periapical healing [ Time Frame: 12 months ]
- Evidence of root development [ Time Frame: 24 months ]
- Evidence of pulp sensibility [ Time Frame: 24 months ]a positive response to pulp sensibility tests include cold test and electric pulp testing
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02801552
|Contact: Yuemin Chen, MDSemail@example.com|
|School and Hospital of Stomatology, Fujian Medical University||Recruiting|
|Fuzhou, Fujian, China, 350002|
|Contact: Yuemin Chen, MDS +8615806033646 firstname.lastname@example.org|
|Study Chair:||Xiaojing Huang, PhD||School and Hospital of Stomatology, Fujian Medical University|