COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC:

Get the latest research information from NIH: Menu

Emotional Brain Processes in Recreational Cannabis Users

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT02801214
Recruitment Status : Completed
First Posted : June 15, 2016
Last Update Posted : February 2, 2017
German Research Foundation
University Hospital, Bonn
Information provided by (Responsible Party):
Benjamin Becker, University of Electronic Science and Technology of China

Brief Summary:
This fMRI study investigates neural correlates of emotion regulation, emotion processing and craving in recreational cannabis users.

Condition or disease Intervention/treatment
Recreational Cannabis Use Other: fMRI

Layout table for study information
Study Type : Observational
Estimated Enrollment : 50 participants
Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Effects of Recreational Cannabis Use on Brain Activation Patterns Associated With Emotional Processes
Study Start Date : May 2015
Actual Primary Completion Date : December 2015
Actual Study Completion Date : December 2016

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Marijuana

Group/Cohort Intervention/treatment
Recreational Cannabis Use
ages 18-40
Other: fMRI
Healthy control subjects
socio-demographically matched
Other: fMRI

Primary Outcome Measures :
  1. fMRI neural correlates of emotional brain processes in recreational cannabis users after 72 hours of abstinence [ Time Frame: one time point = fMRI assessment after 72 hours of abstinence ]
    Activation patterns in brain regions known to be involved in emotional processing and to be altered by cannabis use (e.g. striatum, prefrontal cortex, insula, ACC)

Secondary Outcome Measures :
  1. Ratings of subjective experience (affect, craving) [ Time Frame: one time point = during fMRI assessment after 72 hours of abstinence ]

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   18 Years to 40 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Recreational male cannabis users

Inclusion Criteria:

  • Recreational cannabis use
  • 72 hours of abstinence

Exclusion Criteria:

  • neurological disorders
  • psychiatric disorders according to DSM-4
Layout table for additonal information
Responsible Party: Benjamin Becker, Prof. Dr. rer. nat. Benjamin Becker, University of Electronic Science and Technology of China Identifier: NCT02801214    
Other Study ID Numbers: ART_Can_02
First Posted: June 15, 2016    Key Record Dates
Last Update Posted: February 2, 2017
Last Verified: February 2017
Keywords provided by Benjamin Becker, University of Electronic Science and Technology of China:
Additional relevant MeSH terms:
Layout table for MeSH terms
Marijuana Abuse
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders