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Risk Factors Associated With Binge Drinking Behaviors Among College Students (AlcoolPredict)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT02794311
Recruitment Status : Completed
First Posted : June 9, 2016
Last Update Posted : June 12, 2020
Sponsor:
Information provided by (Responsible Party):
CHU de Reims

Brief Summary:
The purpose of this study is to specify the psychological, cognitive, neuro-functional and genetic profile associated with binge drinker behaviors among young adults. Results will help identifying more precisely vulnerability factors associated with this pattern of alcohol consumption and guiding prevention efforts.

Condition or disease Intervention/treatment Phase
Binge Drinking Other: Alcoolpredict Not Applicable

Detailed Description:
Binge drinking behavior is characterised by speed of drinking on a particular occasion, frequency of drunkenness during the most recent six month period, and the percentage of times getting drunk when drinking. The prevalence of weekly binge drinking among European Union drinkers in 2009 was reported to be 28% of the student population, and 33% among all young people aged 15-24. The consequences of this behavior are multiple and often dramatic, they include: academic failure, violent acts, rape, domestic or road accidents. The study aims to identify vulnerability factors associated with binge drinking. The protocol explores the psychological (personality), neuropsychological (executive functions, memory), genetic (snp polymorphisms) and neuro-anatomical (fMRI) patterns associated with binge drinking behavior.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 125 participants
Allocation: N/A
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Health Services Research
Official Title: AlcoholPredict: Neuropsychology, Brain Imaging and Genetic Polymorphisms in Binge Drinking
Study Start Date : February 2015
Actual Primary Completion Date : September 24, 2019
Actual Study Completion Date : September 24, 2019

Intervention Details:
  • Other: Alcoolpredict
    psychological (personality), neuropsychological (executive functions, memory), genetic (snp polymorphisms) and neuro-anatomical (fMRI)


Primary Outcome Measures :
  1. Neuropsychological test : Mini International Neuropsychiatric Interview (M.I.N.I) [ Time Frame: day 1 ]
  2. Neuropsychological test : Wisconsin Card Sorting Test (WCST) [ Time Frame: V2(3 weeks later) ]
  3. Genetics tests (Single Nucleotide Polymorphism) [ Time Frame: V2(3 weeks later) ]
  4. MRI - signal BOLD (" Blood Oxygen Level Dependant "). [ Time Frame: V3(up to 2 month) ]
  5. Neuropsychological test : Family Informant Schedule and Criteria (FISC) [ Time Frame: day 1 ]
  6. Neuropsychological test : Alcohol Use Questionnaire [ Time Frame: day 1 ]
  7. Neuropsychological test :Trail Making Test, partie A et B [ Time Frame: V3(up to 2 month) ]
  8. Neuropsychological test : Plus/Minus Test [ Time Frame: V3(up to 2 month) ]
  9. Neuropsychological test :Go/No-Go [ Time Frame: V3(up to 2 month) ]


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Ages Eligible for Study:   18 Years to 25 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion criteria :

  • Males or females
  • Right-handed
  • Aged 18-25 years
  • Native French speaker, able to read French and complete study evaluations
  • Caucasian
  • Able to provide informed written and verbal consent

Exclusion criteria

  • A significant general medical illness, including neurological disorders, mental retardation or head trauma
  • Depression, bipolar disorder, schizophrenia or schizoaffective disorder diagnostic according to DSM-IV
  • Handling of psychotropics substances
  • A sensorial impairment (visual and/or hearing)
  • Women who are pregnant
  • Contraindication to the use of MRI (pacemaker, metal in their body)

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02794311


Locations
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France
Chu Reims
Reims, France, 51092
Sponsors and Collaborators
CHU de Reims
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Responsible Party: CHU de Reims
ClinicalTrials.gov Identifier: NCT02794311    
Other Study ID Numbers: PO13129
First Posted: June 9, 2016    Key Record Dates
Last Update Posted: June 12, 2020
Last Verified: June 2020
Additional relevant MeSH terms:
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Binge Drinking
Mental Disorders
Alcohol-Related Disorders
Substance-Related Disorders
Chemically-Induced Disorders
Alcohol Drinking
Drinking Behavior