Oral Contraceptives as Infertility Treatments for Premature Ovarian Failure
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|ClinicalTrials.gov Identifier: NCT02757469|
Recruitment Status : Not yet recruiting
First Posted : May 2, 2016
Last Update Posted : May 2, 2016
|Condition or disease||Intervention/treatment||Phase|
|Primary Ovarian Insufficiency Menopause, Premature||Drug: Drospirenone and ethinyl estradiol combination (Yasmin)||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||20 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Drospirenone and Ethinyl Estradiol Combinations (Yasmin) as Infertility Treatments for Premature Ovarian Failure: a Perspective Follow-up Study.|
|Study Start Date :||May 2016|
|Estimated Primary Completion Date :||May 2020|
|Estimated Study Completion Date :||May 2021|
Pregnancies will occur while the women are taking oral contraceptives (Yasmin). The possible role of exogenous estrogens in sensitizing the granulosa cells to the effect of follicle-stimulating hormone and thereby inducing ovulation and conception in some women with premature ovarian failure is examined.
Drug: Drospirenone and ethinyl estradiol combination (Yasmin)
Female oral combined contraceptive containing 30 mcg (0.030 mg) Ethinyl Estradiol and 3 mg drospirenone (Androstenes)
- live birth [ Time Frame: 3 years ]The event that a FETUS is born alive with heartbeats or RESPIRATION regardless of GESTATIONAL AGE. Such liveborn is called a newborn infant (INFANT, NEWBORN).
- clinical pregnancy rate [ Time Frame: 3 years ]The ratio of the number of conceptions (CONCEPTION) including LIVE BIRTH; STILLBIRTH; and fetal losses, to the mean number of females of reproductive age in a population during a set time period.
- multiple pregnancy [ Time Frame: 3 years ]The condition of carrying two or more FETUSES.
- miscarriage [ Time Frame: 3 years ]Expulsion of the product of FERTILIZATION before completing the term of GESTATION and without deliberate interference.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02757469
|Contact: Yunhai Chuai, Drfirstname.lastname@example.org|
|Navy General Hospital|
|Beijing, Beijing, China, 100048|
|Contact: Yunhai Chuai, Dr +86-18810892004 email@example.com|
|Principal Investigator: Wei Shang, Dr|
|Principal Investigator: Lei Chen, Dr|
|Principal Investigator: Yunhai Chuai, Dr|
|Sub-Investigator: Mingming Shu, Dr|
|Sub-Investigator: Ming Zhou, Dr|
|Sub-Investigator: Mengnan Chen, Dr|
|Sub-Investigator: Huiming Han, Dr|
|Principal Investigator:||Wei Shang, Dr||Navy General Hospital, Beijing|