The Impact of Epilepsy Surgery on Dream Content
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|ClinicalTrials.gov Identifier: NCT02731443|
Recruitment Status : Active, not recruiting
First Posted : April 7, 2016
Last Update Posted : August 13, 2018
|Condition or disease||Intervention/treatment|
|Dream Content||Procedure: Epilepsy surgery Procedure: Depth electrodes insertion|
Show Detailed Description
|Study Type :||Observational|
|Estimated Enrollment :||60 participants|
|Official Title:||The Impact of Epilepsy Surgery on Dream Content|
|Actual Study Start Date :||March 2016|
|Actual Primary Completion Date :||July 2018|
|Estimated Study Completion Date :||December 2018|
Epilepsy patients undergoing elective surgical resection of brain tissue; study group: epilepsy surgery=ESx.
Procedure: Epilepsy surgery
Epilepsy surgery is a procedure that removes an area of the brain where seizures originate.
Epilepsy patients undergoing elective depth electrodes insertion in general anesthesia; control group: depth electrodes=DE.
Procedure: Depth electrodes insertion
Depth electrodes are inserted for monitoring/mapping the subsurface levels of the brain for the surgical treatment of epilepsy.
- Percentage Change of Dream Features Occurrence (i.e. dream content; MOST RECENT DREAM questionnaire) - both groups (ESx & control group) [ Time Frame: 3 months ]
Percentage change of the following dream features occurrences according to the Hall/Van de Castle system are considered:
- Social Interactions
- Activities (walking, talking, seeing, thinking, etc.)
- Success and Failure
- Misfortune and Good Fortune
- Descriptive Elements (modifiers, time, negatives)
The relative abundance of the dream content listed above will be expressed in percentage and postoperative changes compared to the preoperative baseline.
Relative differences between the indicators will be determined and statistically tested for significance. The one indicator that turns out to be statistically different from the rest will be considered the primary outcome measure. For an example, compare Bentes et al. 2011.
- Dream Content (MOST RECENT DREAM questionnaire) - ESx group [ Time Frame: 12 months ]Major indicators for main content categories according to the Hall/Van de Castle system.
- Seizure frequency (ESx only) [ Time Frame: 3 and 12 months ]According to the ENGEL classification
- Anti epileptic drugs (AED) usage (ESx only) [ Time Frame: 3 and 12 months ]Number of different AED
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02731443
|London Health Sciences Center, University Hospital|
|London, Ontario, Canada, N6A 5A5|
|Principal Investigator:||David A Steven, M.D.||London Health Science Center|